摘要
目的:观察心理应激对大鼠颞下颌关节(temporomandibularjoint,TMJ)的影响及其病理改变。方法:90只SD大鼠,随机分为3组:对照组,心理应激组和足部电击组。每组分别在1、3、5周后观察大鼠的关节盘,髁突及翼外肌的显微和超微结构,并与正常组动物进行比较。结果:心理应激组动物的TMJ出现明显的病理性改变,扫描电镜显示1周时髁突深面胶原纤维暴露,裂缝周围纤维排列紊乱。颞下颌关节盘及髁突均出现胶原纤维断裂,其中3周组动物病理性改变最为严重,可见翼外肌细胞线粒体水肿,严重者出现空泡样变5周时出现适应性表现。结论:长期的心理应激可引起TMJ发生病理性改变,但随着心理应激时间的延长,关节可能会出现一定程度的修复,这可能与动物的适应性有关。
Objective：To observe the influence of emotional stress on the temporomandibular joint（TMJ） of SI） rats. Methods. Standard animal model of emotional stress was created by emotion communication emergency box technique in 30 SD rats and flint-shocked in another 30. Control rats were 30 without treatment, The microstructure and ultrastrueture of the disc surface, condylar surface and external pterygoid muscle were observed 1 , 3 and 5 weeks after emotional stress treatment. Results： Obviously pathological changes were observed in the experimental animals, especially at 3 weeks, involving the fissures on the disc and condylar surface, the collagen fibers were disordered. Electron microscopy observation showed that condylar collagen was exposed. The mitochondtria edema and vacuolar degeneration in the external pterygoid muscle were found. At 5 weeks, the condylar cartilage started to recover. Conclusion：Long term emotional stress may lead to pathological changes of the temporomandibular system. The changes can be partly recovered after a certain time of adaption of TMJ.
出处
《实用口腔医学杂志》
CAS
CSCD
北大核心
2006年第6期841-844,共4页
Journal of Practical Stomatology
关键词
颞颌关节
心理应激
超微结构
Temporomandibular joint
Emotlonal stress
Ultrastructure
