摘要
目的探讨呼吸科病房下呼吸道医院感染病原菌的分布和耐药特征,指导临床合理用药。方法收集从呼吸科患者痰液标本中分离的159株病原菌,进行细菌鉴定和药敏实验,并对革兰阴性杆菌进行ESBLs的检测。结果呼吸道感染病原菌以革兰阴性杆菌为主(69.8%),列前5位的是铜绿假单胞菌(14.5%)、肺炎克雷伯菌(13.8%)、不动杆菌属(10.7%)、金黄色葡萄球菌(10.7%)和真菌(9.4%);产ESBLs革兰阴性杆菌的检出率为10.8%。结论革兰阴性杆菌为呼吸科病房医院感染的主要病原菌,对常用抗菌药物耐药率呈上升趋势,细菌培养和药物敏感性分析,对合理选用抗菌药物,治疗呼吸道感染具有重要意义。
OBJECTIVE To determine the distribution and drug resistance characteristic of pathogens from nosocomial lower respiratory tract infection in wards of respiratory disease and direct clinical doctors to select antibiotics correctly. METHODS A total of 159 strains of pathogens from sputum samples of patients with respiratory tract infection in wards of respiratory disease in our hospital were identified and the drug resistance tests were performed. In addition, ESBLs-producing G^- bacilli were also detected. RESULTS Among 159 strains from respiratory tract infection, G^- bacilli rated the top one （69.8%）, The most common pathogens were Pseudomonas aeruginosa （14. 5%）, Klebsiella pneumoniae （13. 8%）, Acinetobacter baumannii （10. 7%）, Staphylococcus aureus （10.7%）, and fungi （9.4%）. 10. 8% G- bacilli produced ESBLs. CONCLUSIONS G^- bacilli are the main infectious pathogens in respiratory infection and antibiotic resistance rates continue to evolve. Therefore bacterial culture and antibiotic susceptibility tests are very important to select antibiotics correctly for treatment of the infections in wards of respiratory disease.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2006年第11期1302-1304,共3页
Chinese Journal of Nosocomiology
关键词
呼吸道
医院感染
病原菌
耐药性
Respiratory tract
Nosocomial infection
Pathogen
Drug resistance
