摘要
目的:观察无创正压通气(NIPPV)治疗慢性阻塞性肺病(COPD)急性加重合并呼吸衰竭的临床效果。方法:42例COPD合并呼吸衰竭患者在常规综合治疗的同时,选用B iPAP呼吸机行无创正压通气,在机械通气前、机械通气后2h作血气分析,并观察临床效果。结果:与治疗前相比,无创正压通气后2h治疗结束时,pH值改善(P<0.05),PaO2上升(P<0.01),PaCO2下降(P<0.01)。34例患者好转出院。2例患者病情加重,家属不同意气管插管而死亡。6例患者病情加重行气管插管机械通气治疗,其中2例死亡,4例成功撤机好转出院。结论:无创正压通气对COPD急性加重合并呼吸衰竭疗效显著,避免了气管插管,减少了呼吸机相关性肺炎。
Objective： To observe the clinical effect of acute respiratory failure associated with chronic obstructive pulmonary disease （ COPD ） treated with noninvasive positive pressure ventilation （ NIPPV ）. Method： 42 respiratory failure associated with COPD cases taked BiPAP ventilator in NIPPV with the normal treated. Taked hemogasometric analysis before, after 2h and observed clinical result. Result： Compared with before, after 2h at end of treating. PH Value improved （ P 〈 0.05 ） , PaO2 elevated （ P 〈 0. 01 ） , PaCO2 decreased （ P 〈 0.01 ）. 34 cases discharged better. 8 cases became more serious, which 4 cases discharged better with invasive ventilation, 4 cases died because the general condition was badly. Conclusion： NIPPV was a significant effect for acute respiratory failure with COPD avoided the tracheal insertion or tracheotomy, decreased ventilator associated pneumonia.
出处
《河北医学》
CAS
2006年第10期969-971,共3页
Hebei Medicine
关键词
无创正压通气
呼吸衰竭
慢性阻塞性肺病
Noninvasive positive pressure ventilation
Respiratory failure
Chronic obstructive pulmonary diseases
