摘要
目的探索腹盆腔晚期恶性肿瘤较好的治疗措施。方法1998年5月至2004年5月将救治的71例晚期腹盆腔恶性肿瘤患者随机分为治疗组和对照组。治疗组36例实施腹腔热化疗配合同步静脉化疗及中药扶正治疗;对照组35例采用单一的静脉化疗。观察两组患者的近期疗效、生活质量、体重、生存期的变化及毒副反应。结果治疗组临床收益率(CR+PR)、生活质量、体重、生存率均较对照组高(P<0.05)。毒副反应也较对照组低(P<0.05)。未见相关并发症的发生。结论疗效对比观察结果表明,应用腹腔热化疗配合同步静脉化疗及中药扶正治疗对晚期腹盆腔肿瘤有较好的治疗作用,比单一静脉化疗效果明显。
Objective To seek a good method for treatment of the abdominal and pelvic cancer in late stage. Methods Seventy-one patients with late-stage abdominal/pelvic cancer treated in this department from May, 1998 to May, 2005 were randomly divided into experimental group and control group. Thirty-six patients of the experimental group accepted the combination treatment with intraperitoneal heat chemotherapy together with intravenous chemotherapy and Chinese medicine supporting therapy, while 35 patients in the control group were treated with intravenous chemotherapy alone. Short-term therapeutic efficacy, quality of life,body weight,survival time and toxic side effects between the two groups were compared. Results The clinical benefit index（ CR ＋ PR） ,quality of life ,body weight and survival rate in the experimental group were better than those in the control group （ P 〈 0.05 ）. There was less toxic and side effects in the experimental group （P 〈 0.05 ） and no related complication was abserved. Conclusions The results indicate that the combination treatment has apparent curative effects on the abdominal and pelvic cancer in late stage and is a method superior to the intravenous chemotherapy alone.
出处
《中国肿瘤临床与康复》
2006年第5期419-421,共3页
Chinese Journal of Clinical Oncology and Rehabilitation
关键词
腹腔/盆腔
肿瘤
热灌注化疗
静脉化疗
中药扶正治疗
Abdomina cavity/pelvic cavity
Neoplasms
Intraperitoneal heat chemotherapy
Intravenous chemotherapy
Chinese medicine supporting therapy
