摘要
目的探讨阔韧带支持-间质细胞瘤的临床病理特征、免疫表型及生物学行为。方法通过光学显微镜、免疫组化等方法对阔韧带支持-间质细胞瘤进行病理组织学观察,并回顾分析相关文献报道。结果该例肿瘤位于左侧阔韧带内。镜下肿瘤呈分叶状,有不成熟的支持细胞排列呈片块状、不规则形或条索状、宽梁状、巢状、实性或空心的小管;莱迪细胞呈单个或簇集存在,细胞浆丰富且嗜酸。免疫组化示CD 99+,CK+,VIM+,EMA+,AE1+。结论阔韧带支持-间质细胞瘤临床非常罕见,根据其组织学和病理学特征,结合免疫组化染色结果可以做出明确诊断。
[ Objective] To explore the clinical pathological features, immunophonotypes and biologic behaviors of Sertoli - Leydig cell tumor in broad ligament, [ Methods] Optical microscopy and immunohistochemistry were applied for pathological observation; retrospective analysis was made on the relevant literature reports, [ Results] The tumor of this case was located in the left broad ligament, The tumor is lobulated under microscope, some immature Sertoli cells were arranged as either amorphous plaques, funicular, broad beam, nest, solid or hollow tubules; Leydig cells existed individually or in clusters, and their eytoplasm was abundant and eosinophilie. The immunohistochemistry indicated CD99 ＋ , CK ＋ , VIM ＋ , EMA ＋ anti AE1 ＋, [ Conclusion] Sertoli - Leydig cell tumor in broad ligament is clinically rare; definite diagnosis can be made according to the histological and pathoh）gical features combined with immunochemic staining result.
出处
《职业与健康》
CAS
2006年第24期2264-2266,共3页
Occupation and Health
关键词
阔韧带
支持-间质细胞
肿瘤
Broad ligament
Sertoli - Leydig cell
Tumor
