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米氮平治疗广泛性焦虑障碍的开放性研究

An Open Trial of Mirtazapine in the Treatment of Generalized Anxiety Disorder.
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摘要 目的 研究米氮平治疗广泛性焦虑障碍(GAD)的疗效和不良反应。方法 对符合CCMD-3广泛性焦虑诊断标准的患者32例使用30~45mg/d米氮平治疗6周,在0、2、4、6周评定汉密尔顿焦虑量表(HAMA,14项),并评定疗效、记录出现的不良反应。结果 米氮平能显著改善GAD患者的精神性焦虑和躯体性焦虑,治疗结束时的显效率达65.6%,有效率达87.5%。最常见的不良反应为思睡和体重增加。结论 米氮平对广泛性焦虑症疗效肯定,不良反应少。 Objective To explore the clinical efficacy and side effects of mirtazapine in the treatment of generalized anxiety disorder. Methods 32 patients who met CCMD-3 criteria for generalized anxiety disorder were involved in this study, They were treated with mirtazapine for six weeks. Efficacy and side effects were evaluated with Hamilton Anxiety Scale (HAMA) before and after treatment, Results The efficacy rate of was 87.5 %, in which 65.6% were improved markedly. Conclusion Mirtazapine is effective drago in the treatment of generalized anxiety disorder and produces fewer side effects.
作者 陈青松
出处 《中国健康心理学杂志》 2006年第6期639-640,共2页 China Journal of Health Psychology
关键词 米氮平 广泛性焦虑障碍 疗效 汉密尔顿焦虑量表 Mirtazapine Generalized anxiety disorder Efficacy HAMA
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