摘要
目的用以讨论试验温度对注射液用卤化丁基橡胶塞不溶性微粒的影响。方法对注射液用卤化丁基橡胶塞在不同的温度下进行试验。结果与结论1.试验温度越高,注射液用卤化丁基橡胶塞的不溶性微粒脱落就越多。2.试验温度对注射液用卤化丁基橡胶塞小微粒(≥10μm)的影响远大于对大微粒(≥25μm)的影响。
OBJECTIVE To discuss the effects of temperature on the unsolvable particles of halogenated butyl rubber stopper for injection. METHODS Halogenated butyl rubber stopper for injection was researched on different temperatures. RESULTS AND CONCLUSION 1. The more higher the temperature was,the more unsolvable particles separate from the halogenated butyl rubber stopper for injection. 2. The test temperature had more influence on the small particles（≥10μm）than on the big particles（≥25μm） of the halogenated butyl rubber stopper for injection.
出处
《齐鲁药事》
2006年第10期624-625,共2页
qilu pharmaceutical affairs
关键词
注射液用卤化丁基橡胶塞
不溶性微粒
温度
Halogenated butyl rubber stopper for injection unsolvable particle temperature
