摘要
由于铬缺乏与2型糖尿病、心血管疾病以及神经系统紊乱等疾病有关,而适量补铬可改善葡萄糖耐量、预防动脉粥样硬化,并增强机体免疫功能。因此,铬作为营养强化剂的安全性研究备受关注。动物实验和人体研究对摄入吡啶甲酸铬及其他三价铬的安全性进行了评价。从非致癌性毒性、潜在致癌性以及生物蓄积性等方面对该领域的研究进展作一综述。
Trivalent chromium deficiency has been associated with such diseases as type 2 diabetes ,cardiovascular disease, and nervous system disorders. Whlie improvement of glucose intolerance, prevention of atherosclerosis, and enhancement of immune function is observed after chromium supplementation. Hence, the study of safety of chromium tripicolinate for addition to foods as a nutrient supplement is needed. In order to evaluate the safety of chromium tripicolinate, the studies examined effects in animals or human clinical trials. In this article, we review the key studies that evaluated the non-carcinogenic toxicity, the potential carcinogenicity, and the bioaceumulation of chromium tripicolinate, as well as other trivalent chromium compounds.
出处
《国外医学（医学地理分册）》
CAS
2006年第3期97-99,共3页
Foreign Medical Sciences：Section of Medgeography
关键词
铬
安全性
毒理学
chromium
safety
toxicity
