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Survivin基因在血管瘤组织中表达的统计学分析 被引量:1

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摘要 目的:探讨Survivin基因在血管瘤组织中的表达及其统计学分析意义。方法:采用免疫组织化学方法检测人皮肤血管瘤增生期、退化期及正常皮肤组织中Survivin基因的表达水平,利用计算机图像分析技术测量不同时期血管瘤组织和正常皮肤组织Survivin基因表达的平均光密度和平均阳性面积。结果:Survivin基因在增生期血管瘤内皮细胞的表达明显高于退化期血管瘤内皮细胞和正常皮肤组织血管内皮细胞(P<0.01);Survivin基因在退化期血管瘤内皮细胞的表达与正常皮肤组织血管内皮细胞相比,差异无显著性(P>0.05)。结论:Survivin基因在血管瘤的发生及血管形成中起了关键作用。
出处 《数理医药学杂志》 2006年第5期511-513,共3页 Journal of Mathematical Medicine
基金 国家自然科学基金资助(课题批准项目编号:30271345) 湖北省科技厅资助(课题批准项目编号:2003ABA164) 湖北省卫生厅资助(课题批准项目编号:JXIB075) 湖北省科技厅资助(课题批准项目编号:2004AA301c107)
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