期刊文献+

危重患者血糖水平的控制 被引量:1

在线阅读 下载PDF
导出
摘要 随机选择398例危重患者分成两组:A组采用皮下注射胰岛素,B组采用微泵或输液泵持续输注胰岛素。每组均分为3个亚组(A1、A2、A3和B1、B2、B3):1组血糖控制在4~6mmol/L,2组血糖控制在6.1~8.9mmol/L,3组血糖控制在9~11mmol/L。观察6个亚组的病死率、住院时间、需肾脏替代治疗的例数、需机械通气治疗的例数、需血管活性药物支持的例数、抗菌药使用时间超过2周的例数等指标。结果A、B两组中第1、2亚组上述指标均较第3亚组明显减少或降低(P〈0.05),而各1、2亚组上述指标在组间和组内相比均无明显差异(P〉0.05)。但在低血糖发生率方面,第1亚组明显高于第2亚组,且A组较B组更甚(A组P〈0.01,B组P〈0.05)。提示采用微泵或输液泵持续输注胰岛素将血糖控制在6.1~8.9mmol/L可缩短住院时间,保护重要脏器的功能,降低危重患者的病死率。
出处 《苏州大学学报(医学版)》 CAS 北大核心 2006年第4期675-676,685,共3页 Suzhou University Journal of Medical Science
  • 相关文献

参考文献11

  • 1van den Berghe G,Wouters P,Weekers F,et al.Intensive insulintherapy in critically ill patients[J].N Eng J Med,2001,345:1359-1367.
  • 2Finney SJ,Zekveld C,Elia A,et al.Glucose control and mortality in critically ill patients[J].JAMA,2003,290:2041-2047.
  • 3Krinsley JS.Association between hyperglycemia and increased hospital mortality in a heterogeneous population of critically ill patients[J].Mayo Clin Proc,2003,78:1471-1478.
  • 4Mizock BA.Blood glucose management during critical illness[J].Rev Ender Metab Disord,2003,4:187-194.
  • 5陈灏珠.实用内科学[M](第10版)[M].北京:人民卫生出版社,1997.835-838.
  • 6Robinson LE,van Soeren MH.Insulin resistance and hyperglycemia in critically illness:role of insulin in glycemic control[J].AACN,2004,15:45-62.
  • 7Chan O,Inouye K,Riddel MC,et al.Diabetes and the hopothalamo-pituitary-adrenal(HPA)axis[J].Minerva Endocrinol,2003,28:87-102.
  • 8Web S.The role of mediators in sepsis reolution[J].Advances in Sepsis,2002,2:8-14.
  • 9Sker RD.The diabetes control and complications trial:implications for policy and practice (Editorial)[J].N Engl J Med,1993,329:1035-1036.
  • 10McMullin J,Brozek J,Jaeschke R,et al.Glycemic control in the ICU:a multicenter survey[J].Intensive Care Med,2004,30:798-803.

共引文献253

同被引文献7

  • 1李官明,张鹤,郭潇静.强化胰岛素治疗的初始剂量探讨[J].中国误诊学杂志,2004,4(9):1463-1464. 被引量:15
  • 2Elan J,Laureal AO,Michael D,et al.The impact of hyperglycim ia on patiens with severe brain injury[J].Trauma,2005;59(1):47-50.
  • 3Vanden Berghe G,Wouters PJ,Weekers F,et al.Intensive insulin therapy in the critically ill patients[J].N Engl J Med,2001 ;345(19): 1359-1367.
  • 4Yendamun S,Fulda GL,Tinkoff GH.Admission hyperglycemia as a prognostic indicator in trauma[J].J Trauma,2003;55:33-38.
  • 5Krinsley JS.Association between hyperglycemia and increased hospital mortality in a heterogeneous population of critically ill patients[J].Mayo Clin proe,2003;78:1471-1478.
  • 6Sker RD.The diabetes control and complications trial:implications tbr policy and practice (Editorial)[J].N Engl J Med,1993;329:1035-1036.
  • 7刘金凤,许丽华.应激性高血糖对综合ICU危重病人预后的影响[J].局解手术学杂志,2008,17(1):33-34. 被引量:18

引证文献1

二级引证文献5

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部