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不同容量急性高容量血液稀释用于围术期老年患者的可行性 被引量:15

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摘要 目的评估对老年患者输注不同负荷容量的6%羟乙基淀粉(HES)实施急性高容量血液稀释(AHH)的安全性和有效性。方法择期全髋置换术患者36例,按输注6%HES15、20和25ml/kg分为Ⅰ组、Ⅱ组和Ⅲ组,每组12例。三组患者均在硬膜外阻滞复合全身麻醉下实施AHH,全麻诱导后,经中心静脉将6%HES以50ml/min输注完毕。术中连续监测心输出量(CO)、心脏指数(CI)、每搏输出量(SV)、外周血管阻力(SVR)、肺血流量(PCBF),同时监测CVP、MAP、HR。记录术中失血量和输液量。结果三组患者的CI、CVP、CO、PCBF及SV,在AHH完毕即刻和术毕较AHH前明显升高(P<0.05)。三组患者的Hb、Hct及血小板在AHH完毕即刻、术毕和术后1d与AHH前相比均降低(P<0.05);Ⅰ组与Ⅱ组患者之间的比较差异均无显著意义。Ⅰ组与Ⅲ组比较,CI、CVP、CO及SV的差异有显著意义(P<0.05);Ⅲ组较Ⅰ组和Ⅱ组的PCBF明显升高(P<0.05)。三组患者的ACT和血乳酸(Lac)在AHH前后差异均无显著意义。结论在硬膜外复合全麻下,对无严重心肺疾病的老年患者,采用6%HES按15ml/kg和20ml/kg以50ml/min快速扩容实施AHH是安全有效的,而25ml/kg对老年患者负荷容量过度。
出处 《临床麻醉学杂志》 CAS CSCD 2006年第8期587-589,共3页 Journal of Clinical Anesthesiology
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参考文献6

  • 1Monk TG,Goodnough LT,Birkmeyer JD,et al.Acute normovolemic hemodilution is a cost-effective alternative to preoperative autologous blood donation by patients undergoing radical retropubic prostatectomy.Transfusion,1995,35:559-565.
  • 2Mielke LL,Entholzner EK,Kling M,et al.Preoperative acute hypervolemic hemodilution with hydroxyethylstarch:an alternative to acute normovolemic hemodilution.Anesth Analg,1997,84:26-30.
  • 3Mortelmans Y,Merckx E,van Nerom C,et al.Effect of an equal volume replacement with 500 ml 6% hydroxyethyl starch on blood and plasma volume of healthy volunteers.Eur J Anaesthesiol,1995,12:259-264.
  • 4孙灿林,姜琳.无创部分二氧化碳复吸技术心输出量测定的临床研究[J].临床麻醉学杂志,2004,20(4):201-203. 被引量:5
  • 5董庆龙,温晓晖,欧阳葆怡.急性高容量血液稀释对血液动力学及血液流变学的影响[J].中华麻醉学杂志,2001,21(5):265-268. 被引量:70
  • 6Fukusaki M,Nakamura T,Miyoshi H,et al.Splanchnic perfusion during controlled hypotension combined with acure hypervolemic hemodilution:a comparision with combination of acute normovolemic hemodilution-gastric intramucosal pH study.J Clin Anesth,2000,12:421-426.

二级参考文献15

  • 1周衍椒 张镜如.生理学,第2版[M].北京:人民卫生出版社,1984.98-104.
  • 2[1]Connors AF Jr,Speroff T,Dawson NV,et al.The effectiveness of right heart catheterization in the initial care of critically ill patients.JAMA,1996,276:889-897.
  • 3[2]Bender JS,Smith-Meek MA,Jones CE.Routine pulmonary artery catheterization does not reduce morbidity and mortality of elective vascular surgery: results of a prospective,randomized trial.Ann Surg,1997,226: 229-237.
  • 4[3]Valtier B,Cholley BP,Belot JP,et al.Noninvasive monitoring of cardiac output in critically ill patients using transesophageal Doppler.Am J Respir Crit Care Med,1998,158:77-83.
  • 5[4]Odenstedt H,Aneman A,Oi Y,et al.Descending aortic blood flow and cardiac output: a clinical and experimental study of continuous oesophageal echo-Doppler flowmetry.Acta Anaesthesiol Scand,2001,45:180-187.
  • 6[5]Preiser JC,Daper A,Parquier JN,et al.Transthoracic electrical bioimpedance versus thermodilution technique for cardiac output measurement during mechanical ventilation.Intensive Care Med,1989,15: 221-223.
  • 7[6]Zollner C,Haller M,Weis M,et al.Beat-to-beat measurement of cardiac output by intravascular pulse contour analysis: a prospective criterion standard study in patients after cardiac surgery.J Cardiothorac Vasc Anesth,2000,14: 125-129.
  • 8[7]Jaffe MB.Partial CO2 rebreathing cardiac output-operating principles of the NICO system.J Clin Monit Comput,1999,15: 387-401.
  • 9[8]de Abreu M,Quintel M,Ragaller M,et al.Partial carbon dioxide rebreathing: a reliable technique for noninvasive measurement of nonshunted pulmonary capillary blood flow.Crit Care Med,1997,25: 675-683.
  • 10[9]van Heerden PV,Baker S,Lim SI,et al.Clinical evaluation of the non-invasive cardiac output (NICO) monitor in the intensive care unit.Anaesth Intensive Care,2000,28: 427-430.

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