摘要
目的比较氨氯地平、依那普利治疗老年1、2级原发性高血压的临床疗效和安全性。方法70例老年1、2级原发性高血压患者随机分为两组,氨氯地平组(n=35)给予氨氯地平5mg/d；依那普利组(n=35)给予依那普利10mg/d。8周后统计疗效。结果治疗后两组疗效间差异无显著性意义(P＞0．05),均可降低收缩压和舒张压,与治疗前比较差异均有显著性意义(P＜0．05),降压幅度组间差异无显著性意义(P＞0．05)。治疗前后对心率影响两组相比差异无显著性意义(P＞0．05)。两组均无严重不良反应。结论氨氯地平和依那普利治疗老年1、2级高血压安全有效,值得推广,可作为一线治疗药物。
Objective To compare the therapeutic effect and security of Amlodipine and Enalapril Tablets in the treatment of the older with 1 - 2 rank of primary hypertension. Methods 70cases older patients with 1 - 2 rank of primary hypertension were randomly divided into two groups （ Amlodipine group, 35cases ; Enalapril Tablets 35cases）. The Amlodipine group was treated with Amlodipine 5mg/d, and the other with Enalapril Tablets 10mg/d. Then, the curative effect and side effect Were analysized and compared after 8 weeks. Results Two kinds of anti - hypertension all can decrease the systolic pressures and diastolic pressures, but the curative effect difference have no significance. In two groups affecting heart rate and the side reactions have no obvious difference. Conclusion Amlodipine and Enalapril Tablets in treating the older with 1 - 2 rank of primary hypertension are safe and effective, worth popularizing.
出处
《实用心脑肺血管病杂志》
2006年第7期552-553,共2页
Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
