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肿瘤患者血清中鸟氨酸脱羧酶的研究 被引量:1

Determination of Serum Ornithine Decarboxylase Activity in Patients with Cancer
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摘要 用高效液相色谱法测定了正常人及乳腺癌、宫颈癌、食管癌、肺癌患者血清中鸟氨酸脱羧酶活性。结果表明,肿瘤患者血清中鸟氨酸脱羧酶的活性升高,P<0.05。其乳腺癌、宫颈癌、食管癌及肺癌的阳性率分别为:75.0%、63.6%、50.0%和42.9%。说明测定血清中鸟氨酸脱羧酶的活性对肿瘤的诊断有一定临床意义。 The serum ornithine decarboxylase (ODC) activity was deter-mined in patients with breast,uterine cervix,esophagus and lung cancers as well as healthy individuals using HPLC. The serum ODC activity in patients with cancer was significantly higher than that in healthy subjects. The postitive rates of ODC in patients with breast, uterine cervix, esophagus and lung cancers were 75. 0%, 63. 6%, 50. 0% and 42. 9% respectively. Determination of ODC activity may be helpful in clinical diagnosis.
出处 《中国肿瘤临床》 CAS CSCD 北大核心 1996年第11期804-806,共3页 Chinese Journal of Clinical Oncology
关键词 鸟氨酸脱装酶 腐胺 高效液相色谱法 肿瘤 Ornithine decarboxylase HPLC Cancer Putrescine
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