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造血干细胞移植治疗自身免疫病机制研究进展 被引量:1

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摘要 造血干细胞移植(HSCT)已用来治疗多种自身免疫病(AD),至2005年底已有近800例难治性AD患者接受了HSCT.目前欧美正在进行HSCT治疗AD的Ⅲ期临床研究。关于HSCT治疗AD的机制有很多假说.如“重建免疫系统”(reseting the immune system)、“逆转免疫时相”(turning back the immunological clock)、“减轻炎症负荷”(debulking of inflammatory load)。本文就近年来HSCT治疗AD的机制作一综述。
出处 《中华风湿病学杂志》 CAS CSCD 2006年第8期501-503,共3页 Chinese Journal of Rheumatology
基金 教育部高校博士点专项基金(20050315001) 江苏省135工程基金(RC2002003) 江苏省自然科学基金(BK2006007)
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