摘要
目的应用短潜时体感诱发电位（SSEP）评价冠心病中枢神经功能的变化.方法刺激43例无明显中枢神经症状的冠心病患者（心绞痛18例、心肌梗死慢性期25例）以及14例正常对照的正中神经,同时记录皮质体感诱发电位和脊髓体感诱发电位,观察中枢神经功能的变化.结果心绞痛和心肌梗死患者的N13、N20、P25波潜伏期及中枢传导时间（CCT）均较对照组明显延长（ P〈0.05～0.001）;心绞痛患者的N20、P25波潜伏期及CCT均较心肌梗死患者明显延长（ P〈0.01～0.001）.结论冠心病特别是心肌梗死患者,其脊髓到大脑皮质第一感觉区的中枢躯体感觉通路存在亚临床损害.
Objective To evaluate central nervous system function of patients with coronary cardiac diease by short latency somatosensory evoked potentials （SSEP）. Methods The cerebral and spinal somatosensory evoked potentials were recorded by stimulating median nerve in 43 patients with coronary cardiac disease but without apparent nervous symptoms and 14 healthy control subjects. Results The lactency periods and central conductive time of N13, N20 and P25 wave were significantly prolonged in patients with myocardial infarction （MI） or angina pectoris （AP） when compared with normal controls （ P〈0.05～0. 001）. The lactency periods and central conductive time of N20 and P25 wave recorded in MI patients were longer than those recorded in AP patients （ P〈0.01～0. 001）. Conclusion The subclinical nervous damages in the central somatosensory pathway from spinal cord to cerebral cortex is present in patients with coronary cardiac disease especially myocardial infarction.
出处
《中国康复理论与实践》
CSCD
2006年第6期471-472,共2页
Chinese Journal of Rehabilitation Theory and Practice
关键词
缺血性心脏病
短潜时体感诱发电位
中枢传导时间
中枢神经系统病变
ischemic cardiac disease
short latency somatosensory evoked potentials
central conductive time
central nervous system disease
