摘要
目的:通过检测2型糖尿病患者血浆P-选择素和血栓调节蛋白水平变化,探讨检测患者血浆P-选择素和血栓调节蛋白的临床意义。方法:采用EL ISA法检测了95例2型糖尿病患者和50例健康对照组血浆P-选择素和血栓调节蛋白水平。结果:2型糖尿病患者血浆P-选择素和血栓调节蛋白水平分别依次升高,且相差显著,与对照组相比有显著性差异(P<0.01);2型糖尿病患者血浆P-选择素与血栓调节蛋白水平呈显著的正相关。结论:检测血浆P-选择素和血栓调节蛋白水平,可作为2型糖尿病并发血管病变、病情判定以及治疗效果观察的指标。
Objective To discuss the clinical significance of examining the changes of blood plasma P-selectin and the plasma thrombomodulin level in the patients with type 2 diabetes mellitus by examining their changes. Methods ELISA method was used to examine the blood plasma P-selectin and plasma thrombomodulin in 95 patients with type 2 diabetes mellitus and 50 health controls. Results The blood plasma P-selectin and level of plasma thrombomodulin were all increased obviously in the patients with type 2 diabetes mellitus compared to controls （P〈0. 01）. The blood plasma P-selectin was positively correlated to the level of plasma thrombomodulin in the patients with type 2 diabetes mellitus. Conclusion To examine the blood plasma P-selectin and level of plasma thrombomodulin can judge the diagnosis, treatment and therapeutic effect of type 2 diabetes mellitus.
出处
《实用诊断与治疗杂志》
2006年第7期507-508,共2页
Journal of Practical Diagnosis and Therapy
关键词
2型糖尿病
P-选择素
血栓调节蛋白
Type 2 diabetes mellitus,P-selectin,plasma thrombomodulin
