摘要
目的分析本地区临床分离菌耐药情况,探讨临床抗菌用药方案,指导临床治疗. 方法对2003年1月～2005年1月临床标本分离出的细菌及其药敏试验作回顾性调查分析. 结果 1 719株病原菌中,G^＋菌563株,占32.8%,G^-菌1 156株,占67.2%.G^＋菌以金黄色葡萄球菌、溶血性链球菌多见.G^-菌以大肠埃希菌、铜绿假单胞菌,肺炎克雷伯菌多见.相当多部分G^＋菌及G^-菌对第三代头孢菌素耐药严重.对G^＋菌最敏感的是万古霉素,对G^-菌最敏感的是泰能. 结论本地区常见致病菌耐药性广泛,临床上应合理用药.用药前药敏试验对指导临床及减少耐药的发生很重要.
Objective To analyze the resistant status of clinically isolated bacteria and provide scientific basis for guidance of clinical treatment in Guangzhou City. Methods Retrospective survey was made on the isolation of bacteria from clinical samples in the Affiliated Hospital of Guangdong Medical College from January 2003 to January 2005 and the results of drug sensitivity tests were analyzed. Results Among the 1 719 pathogenic bacteria isolated 563 strains were gram - positive bacteria with a positive rate of 32.8 % and 1 156 strains were gram - negative bacteria accounted for 67.2 %. Staphylococcus a ureus was the predominated strains of gram positive bacterium and hemolytic streptococcus; while Escherichia coli, Pseudomonas aeruginosa and KlebsieUa pneumoniae were predominated. A lot of strains of gram - positive bacteria and gram - negative bacteria were strongly resistant to cephalosporin. Gram positive and gram negative bacteria were most sensitive to vancomycin and imipenem, respectively. Conclusion The resistance of local bacteria to antibiotics are serious and drug sensitivity tests be conducted to guide clinical use of drugs and delay the development of drug resistance.
出处
《中国热带医学》
CAS
2006年第6期1056-1057,1000,共3页
China Tropical Medicine
关键词
病原菌
耐药性
抗生素
Pathogenic bacteria
Drug resistance
Antibiotics
