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146例慢性肾功能衰竭患者临床分型及相关生化指标研究 被引量:33

Study on Clinical Syndrome Classification and Related Biochemical Indexes in 146 Cases of Chronic Renal Failure
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摘要 目的:观察慢性肾功能衰竭(CRF)中本虚证、标实证所占比例以及相兼情况,分析中医证型与相关生化指标的关系。方法:对146例CRF患者进行中医辨证,并检测相关生化指标,对数据采用单因素方差分析组间比较统计。结果:(1)本虚证中以脾肾气阴两虚证最多,标实证中以湿热证最多;(2)标实证中湿浊证患者血清肌酐、尿素氮均显著高于湿热证和血瘀证;(3)血瘀证患者纤维蛋白原显著高于湿热、湿浊两证。结论:CRF的发生、发展与湿证关系密切,多表现为湿浊、湿热、血瘀、湿瘀等标实证型,在生化指标上主要与肾功能、血液动力学等异常有关。 Objective:To observe the ratio of the syndrome of deficiency in origin to the syndrome of excess in superficiality in chronic renal failure (CRF)and co-existent states,and to analyze the relationship between TCM syndrome types and related biochemical indexes, Methods :TCM syndrome differentiation was carried out and related biochemical indexes were determined in 146 cases of CRF, The data were compared and analyzed with single factor analysis of variance between groups, Results.. (1)Deficiency of both qi and yin of spleen and kidney was the most frequently-appeared type in the deficiency syndrome,and damp-heat syndrome was the most frequently-appeared type in the excess syndrome; (2)Serum creatinine(SCr)and blood uria nitrogen(BUN)in the patient of damp-turbid syndrome in the excess syndrome were significantly higher than those in the patient of damp-heat and blood stasis syndrome; (3)Fibrin in the patient of blood stasis was significantly higher than that in damp-heat syndrome and damp-turbid syndrome. Conelusion..Generation and development of CRF are closely related with dampness syndrome, usually marked by syndrome of damp-turbid, damp-heat, blood stasis, damp-stagnation, and was mainly related with abnormal renal function and hemorheologic indexes in the biochemical indexes.
出处 《中医杂志》 CSCD 北大核心 2006年第5期374-377,共4页 Journal of Traditional Chinese Medicine
关键词 肾功能衰竭 慢性/血液 辨证分型 Renal failure ,chronic/blood TCM syndrome classification
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