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2型糖尿病视网膜病变危险因素分析 被引量:12

AN ANALYSIS OF RISK FACTORS OF DIABETIC RETINOPATHY IN PATIENTS WITH TYPE 2 DIABETES
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摘要 目的 探讨2型糖尿病并发视网膜病变的危险因素.方法 应用Logistic多因素回归方法,分析124例2型糖尿病病人的病程、血压、血糖、血脂等13个因素与糖尿病视网膜病变间的相关性.结果 2型糖尿病并发视网膜病变组与无视网膜病变组比较有更长的病程,较高的空腹血糖、餐后2 h血糖和糖基化血红蛋白(t=2.369~5.870,P〈0.05、0.01);糖尿病病程、糖基化血红蛋白与视网膜病变的发生呈显著正相关(OR=1.157、1.471,P〈0.05).结论 病程、糖基化血红蛋白是2型糖尿病视网膜病变的危险因素,控制高糖血症有助于防止视网膜病变的发生和发展. Objective To study the risk factors of diabetic retinopathy (DR) in patients with type 2 diabetes mellitus (DM), Methods This study involved 124 type 2 diabetic patients. The correlation of 13 factors, such as the course of the disease, blood pressure, blood glucose, blood lipid, etc. , with DR were analyzed by Logistic regression. Results Compared with diabetic patients without retinopathy, those complicated with retinopathy had longer course, higher fasting blood glucose and 2-h-after-meal blood glucose concentration and higher glycated hemoglobin (t=2. 369 5. 870, P〈0. 05,0. 01). DR was positively correlated with the course of the disease and glycated hemoglobin (OR= 1. 157, 1. 471 ,P〈0. 05). Conclusion Both the course of DM and glycated hemoglobin arc risk factors of DR. Control of hyperglycemia is conducive to prevention of the development of the complication.
出处 《齐鲁医学杂志》 2006年第3期243-244,共2页 Medical Journal of Qilu
关键词 糖尿病 2型 糖尿病视网膜病变 危险因素 diabetes mellitus, type 2 diabetic retinopathy risk factors
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参考文献2

  • 1童南伟.糖尿病慢性并发症的临床研究及其现代认识[J].实用糖尿病杂志,1997,15:207-207.
  • 2MCCARTER R J,HEMPE J M,GOMEZ R,et al.Biological variation in HbAlc predicts risk of retinopathy and nephropathy in type 1 diabetes[J].Diabetes Care,2004,27(6):1259-1264.

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