摘要
5-溴乙酰基水杨酰胺是一种非常重要的医药与农药中间体。选择溴在乙酸溶剂中,5-乙酰基水杨酰胺溴化。当反应物n(5-乙酰基水杨酰胺)∶n(溴)=1∶1.05,5℃反应12h,可高选择性得到5-溴乙酰基水杨酰胺,收率93.2%。
5- （Bromoacetyl） salicylamide is an important intermediate of medicine and pesticide. 5-Acetyl salicylamide was brominated by bromine to give 5-（bromoacetyl）-salicylamide in high selectivity. The yield was 93.2% when the molar ratio of 5-acetyl sallcylamide to bromine was 1 ： 1.05 at 5 ℃ for 12 h.
出处
《精细化工中间体》
CAS
2006年第2期32-33,共2页
Fine Chemical Intermediates
