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自然流产妇女血清氧化应激状态分析 被引量:1

An analysis of oxidative stress in serum of pregnant women with abortion.
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摘要 目的通过对自然流产女妇血清氧化应激指标———超氧化物歧化酶(SOD)、丙二醛(MDA)及维生素E(VE)的测定,分析其氧化应激状态。方法用化学比色法对20例正常未孕妇女、20例正常孕早期妇女及20例自然流产妇女血清中SOD、MDA及VE进行测定。结果与未孕妇女相比,正常孕早期妇女血清MDA升高(P<0.05),SOD和VE也显著升高(P<0.05;P<0.05);与正常孕早期妇女相比。自然流产妇女血清MDA水平升高(P<0.05),SOD、VE水平却下降(P<0.05;P<0.05)。结论自然流产妇女处于氧化应澈状态中。 Objective :To determine the levels of maternal serum SOD, MDA and VE in patients with abortion in order to analyze their oxidative stress. Methods:The levels of maternal serum SOD, M DA and VE were measured in 20 healthy non -pregnant women ,20 normal early pregnant women and 20 patients with abotrion by chemocoiorimetry. Results :The levels of maternal serum MDA in normal early pregnant Women were significantly higher than those of non - pregnant women ( P 〈 0. 05), so were the levels of SOD and VE ( P 〈0. 05, P 〈0. 05) ;the levels of maternal serum MDA in patients with abortion were also higher than those of normal early pregnant women( P 〈0. 05), while the levels of SOD and VE were significantly decreased( P 〈0. 05, P 〈0. 05). Conclusion:The pregnant women with abortion were in oxidative stress.
出处 《中国优生与遗传杂志》 2006年第5期85-85,116,共2页 Chinese Journal of Birth Health & Heredity
关键词 氧化应激 自然流产 超氧化物歧化酶 丙二醛 维生素E Oxidative stress Abortion Superoxide dismutase Malondialdehyde Vitamin E
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