摘要
目的在保证孕妇安全的前提下延长胎龄,使胎儿能达到或更接近成熟,从而提高胎儿的存活率。方法将320例患者随机分为治疗组和对照组。治疗组首先用25%硫酸镁20m l加入10%葡萄糖液500m l,静脉点滴,1h滴完,然后,用25%硫酸镁16m l加入10%葡萄糖液500m l,静脉点滴,维持5h,每日1次;对照组用止血芳酸针0.3g加入10%葡萄糖液500m l,静脉点滴,每日1次,止血敏针0.5g,肌肉注射,每日2次。结果硫酸镁用于前置胎盘期待疗法有效率(92.5%)明显高于对照组(50%),差异有显著意义(P<0.01);两组各孕周组治疗有效率比较,差异有显著意义(P<0.01,P<0.05);本组治疗,无1例死亡。结论硫酸镁用于前置胎盘期待疗法效果好,有效率高。无论孕周长短、出血量多少,用硫酸镁治疗均优于用止血药。而且硫酸镁用于前置胎盘期待疗法是安全有效的,定时作血清镁离子测定则更安全。
Objective On condition that safety is ensured for pregnant women, the expectant therapy can prolong the foetus, age and make the foetuses reach or more close to maturity. Thus it will improve the survival rate of the foetuses. Methods 320 cases of patients were divided randomly into two groups： 160 cases are treated with Epsom salt as the treating group, Another 160 cases are treated with Haemonstatic as the contrasting group. The treating group, first, put 20ml of 25% Epsom salt into 500ml of 10% G. S, I. V. T, and finishing it in an hour. Then, put 16ml of 25% Epsom salt into 500ml of 10% G. S, I. V. T, and keeping 5 hours, once daily. The contrasting group, put 0.3g of Para - aminobenzoic acid into 500ml of 10% G. S, I. V. T, once daily and 0.5g of Dicynonum, i.m. , twice daily. Effective： The foetuses are mature or pregnancy reaches 37 weeks. The pregnant women and their babies are all alive. Invalid： The foetuses die after birth or die in the uterus. Results The efficiency of the treating group can reach 92.5% and obviously is higher than that of contrasting group （50%）. The difference is extremely remarkable （ P 〈0.01）. Compare the efficiency of treatment of two groups for gestational weeks. The difference has remarkable meanings （ P 〈 0.01, P 〈 0.05 ）. The treating group not one patient dead. Conclusion The expectant therapy with Epsom salt for placenta previa has a better result and is more efficient. No matter how long or short the gestational weeks are or no matter how much the bleeding volume is, the treatment with Epsom salt is superior to the treatment of Haemonstatic, so the expectant therapy with Epsom salt for placenta previa is safe and effectual. It is safer to examine serum Mg^2＋ regularly.
出处
《医药论坛杂志》
2006年第4期28-29,共2页
Journal of Medical Forum
关键词
前置胎盘
硫酸镁
期待疗法
疗效
Placenta previa
Epsom salt
Expectant therapy
Curative effect
