摘要
以脱镁叶绿酸-a甲酯1为原料,在酸性条件下加热,将其转化为焦脱镁叶绿酸-a甲酯2.选择四氧化锇为氧化剂将其3-位乙烯基氧化成甲酰基,在碱性条件下,与姜黄素进行Knoevenagel缩合反应,得到联有姜黄素化学结构的卟吩衍生物4.所得叶绿素衍生物均经UV、IR1、H NMR及元素分析证明其分子结构..
Methyl pheophorbide-α was used as starting material and converted into methyl pyropheophorbide-α 2 by heating under acid condition. The vinyl group was oxidized into formyl group with osmium oxide and sodium peridate to give methyl pyropheophorbide - d 4the Knoevenagel reaction of this chlorin aldehyde with curcumin was carried out to complete the synthesis of methyl pyropheophorbide -α with curcumin chemical structures The structures of all these new compounds were characterized by elemental analysis, UV, IR and ^1H NMR spectra.
出处
《通化师范学院学报》
2006年第2期58-60,共3页
Journal of Tonghua Normal University
基金
吉林省教育厅"十五"规划科研项目
