雄激素全阻断在前列腺癌治疗中的应用
摘要
目的了解雄激素全阻断方法在前列腺癌治疗中的作用。方法睾丸切除加氟他胺治疗C、D期前列腺癌患者29例,应用(LHRH-A)加氟他胺治疗3例。结果雄激素全阻断疗法在降低PSA及缩小前列腺体积上有显著疗效。结论在前列腺癌的治疗中,雄激素全阻断治疗疗效好。
出处
《齐齐哈尔医学院学报》
2006年第2期171-171,共1页
Journal of Qiqihar Medical University
参考文献6
-
1吴阶平.泌尿外科学[M].济南:山东科学技术出版社,2004.784-786.
-
2鲍镇美.晚期前列腺癌的治疗新动向[J].中华泌尿外科杂志,2002,23(2):69-71. 被引量:47
-
3Slack NH,Murphy GP.Criteria for evaluating patient responses to treatment modalities for prostate cancer[J].Urol Clin of North Am,1984,11:337-342
-
4Labrie J,Albert J.Comparison of prostatic cancer tissue dihydrotestosterone levels at the time of relapse following orchiectomy or estrogen the rapy[J].J Urol,1984,132:693-696
-
5Lundgren R.Flutamide as primary treatment for metastatic prostatic cancer[J].Br J Urol,1987,59:156-158
-
6David C,Smith MD.Secondary hormonal therapy[J].Seminars in Urology Oncology,1997,15:3-12
二级参考文献10
-
1ShenfeldO,SchellhammerPF.Androgendeprivationtherapy[].Pro staticdisease.2000
-
2Chawnshang Chang.A dominant negative mutant of androgen receptor coactivator ARA54, suppresses androgen receptor transactivation in prostate cancer cell[].J Urol th AUA meeting #.
-
3Prehen RT.On the prevention and therapy of prostate cancer by androgen administration[].Cancer Research.1999
-
4Umekita Y,Kolontis JM,Shutsung L.Human prostate tumor growth in athymic mice-inhibition by androgen and stimulation by finasteride[].Proceedings of the National Academy of Sciences of the United States of America.1996
-
5Hai Yen E,Shiming Chang,Chung WK,et al.Androgen-repressed phenotype in human prostate cancer[].Proceedings of the National Academy of Sciences of the United States of America.1996
-
6Din Lii Lin,Zhi Yao,Keller ET.Interleukin-6 induces androgen responsiveness in prostate cancer cells through up-regulation of androgen receptor expression[].Clinical Cancer Research.2001
-
7Okamoto M,Lee C,Oyasu R.Interleukin-6 as a paracrine and autocrine growth factor in human prostatic carcinoma cells in vitro[].Cancer Research.1996
-
8Hobisch A,Klocker H,Culig Z,et al.Interleukin-6 regulates prostatespecific protein expression in prostate carcinoma cells by activation of the androgen receptor[].Cancer Research.1998
-
9Chen T,Wang LH,Farrar WL.Interleukin 6 activates androgen receptor-mediated gene expression through a transducer and activator of transcription 3-dependent pathway in LNCaP prostate cancer cells[].Cancer Research.2000
-
10Peter C,Smith,Keller ET.Anti-interleukin-6 monoclonal antibo dy inhibits prostate cancer growth in vivo[].nd meeting of AACR New Orleans LA.2001
共引文献471
-
1钟亮,赖海标,黄智峰,曾晔,赖伟业,伍伟超.中西医结合治疗晚期前列腺癌疗效观察[J].现代中西医结合杂志,2005,14(4):480-480. 被引量:5
-
2华立新,吴宏飞,眭元庚,徐正铨,张炜,钱立新,居小兵,张杰秀.比卡鲁胺治疗激素抵抗性前列腺癌[J].中华泌尿外科杂志,2005,26(6):383-385. 被引量:9
-
3王志强,梁大用.晚期前列腺癌的内分泌及放射治疗探讨[J].宁夏医学杂志,2005,27(4):219-221. 被引量:2
-
4钱余,夏仁惠,周伟邦,刘剑新,田长海,韩孝洲,张勇.老年高危患者中晚期前列腺癌的治疗[J].现代泌尿外科杂志,2005,10(3):145-147. 被引量:1
-
5邓京平,许进,万奔.26例老年晚期前列腺癌患者并发症的处理[J].中华老年医学杂志,2005,24(7):511-513. 被引量:2
-
6杨立杰,张士祥,李耀宗,张立民,方强.输尿管阴性结石的ESWL治疗[J].中国医刊,2005,40(8):39-40.
-
7刘玲,谷波,胡艳.TVT治疗女性压力性尿失禁围手术期护理20例[J].华西医学,2005,20(3):567-567. 被引量:1
-
8任仲为,马际春,黎宝莲.激素治疗晚期前列腺癌26例临床观察[J].天津医药,2005,33(9):611-612.
-
9宋有军.下腔静脉后输尿管的诊治体会[J].实用诊断与治疗杂志,2005,19(11):849-850.
-
10张兴林.附睾结核的误诊分析[J].临床军医杂志,2005,33(6):775-775.
-
1吴士良,那彦群,金杰,薛兆英,郭应禄.雄激素全阻断与单纯雄激素受体阻滞剂在前列腺癌治疗中的比较[J].中华泌尿外科杂志,1999,20(1):39-40. 被引量:18
-
2邵立钦,范锐,岳俊敏,牛俊豪,张昊,万久恺,王朝阳.手术去势联合间歇性雄激素全阻断疗法治疗局部进展期前列腺癌的疗效[J].中国老年学杂志,2015,35(14):3934-3935. 被引量:7
-
3赵旭.手术去势联合间歇性雄激素全阻断疗法治疗局部进展期前列腺癌的临床疗效观察[J].中国实用医药,2016,11(4):160-161. 被引量:6
-
4钟狂飚,李维,桂明,龙智,何乐业.雄激素全阻断对前列腺癌患者下尿路症状的改善作用[J].中南大学学报(医学版),2011,36(9):849-853. 被引量:4
-
5黄毅,马潞林,王俊杰,冉维强.^(125)I放射粒子植入结合雄激素全阻断治疗中晚期前列腺癌[J].中国老年学杂志,2005,25(3):267-268. 被引量:4
-
6严维刚,李汉忠,周毅,纪志刚,王惠君.雄激素全阻断治疗对前列腺体积的影响及相关因素分析[J].中华泌尿外科杂志,2006,27(8):556-558. 被引量:12
-
7王卫国,赵伟,鹿占鹏,庞亚彤,杜敬民.雄激素全阻断治疗晚期前列腺癌生存分析[J].济宁医学院学报,2004,27(4):65-66.
-
8张明.联用手术去势法和间歇性雄激素全阻断法治疗前列腺癌的效果探析[J].当代医药论丛,2017,15(1):88-89. 被引量:1
-
9马文波,武俊平,马琳,宋文华,霍墨林.手术去势联合间歇雄激素全阻断疗法治疗晚期前列腺癌的作用观察[J].河北医学,2014,20(9):1457-1459. 被引量:13
-
10汪灶昆,陈卫民,顾继礼,李俊,栾翠芳,戴雨梅,陈仪,王国成.TUVP联合去势术及雄激素阻断治疗晚期前列腺癌疗效观察[J].山东医药,2007,47(21):44-45. 被引量:4