摘要
目的观察危重病患者血乳酸水平的变化及其与APACHEⅡ评分的关系及意义。方法选择在急救中心住院的危重病患者98例,在入院24h内对每个患者进行APACHEⅡ评分,同时抽静脉血测血乳酸水平,按照预后分为死亡组20例,存活组78例。男选取门诊健康体检者印例为对照组,测定静脉血乳酸水平。结果危重病患者血乳酸水平明显高于对照组,两组分别为(6．15±3．99)mmoL／L和(1．68±0．76)mmoL／L,P<0．01。危重病患者APACHEⅡ各分段血乳酸水平与病死率随APACHEⅡ评分的增加而增加,血乳酸水平与APACHEⅡ评分呈显著正相关关系(r=0．768,P<0．01)。死亡组血乳酸水平及APACHEⅡ评分高于存活组。结论危重病患者血乳酸水平和APACHEⅡ评分呈正相关关系,其水平对判断病人的病情和预后有重要意义。
Objective To investigate the relationship between changes of blood lactic acidosis levels and APACHE Ⅱ score m critically ill patients. Methods A severity of illness score （APACHE Ⅱ ）was determined for 98 critically ill patients during the first 24h in the hospital, at the same time, the levels of serum lactic acidosis were measured. All these patients were divided into two groups, based on their prognosis,survival group （n = 78） and death group （n = 20）. 60 healthy volunteers were selected as normal group （n = 60） . Results The levels of serum lactic acidosis in critically ill patients were higher than those in normal group, （6.15 - 3.99）mmol/L VS （ 1.68 ±0.76）retool/L, （ P 〈 0.01）. There was a positive correlation between the levels of serum lactic acidosis and APACHE Ⅱ score （ r = 0. 768, P 〈 0.01 ） An increase in the levels of serum lactic acidosis was associated with aa increase in the severity of illness. The levels of serum lactic acidosis of the death group was higher than that of the survival group （ P 〈0.01）. Conclusion The levels of serum lactic acidosis of severely ill patients is positively correlative with the APACHE II score and the levels play important role in estimation of development and prognosis of illness.
出处
《中国热带医学》
CAS
2006年第3期466-467,共2页
China Tropical Medicine
