摘要
目的探讨建立犬颈总动脉囊状动脉瘤模拟人体颅内动脉瘤的可行性。方法采用外科手术方法建立犬颈动脉囊状侧壁动脉瘤模型。结果建立20条健康实验犬颈动脉囊状侧壁动脉瘤模型40枚,血管造影证实动脉瘤与载瘤动脉均通畅者有36枚,4枚动脉瘤腔自发性完全性闭塞,但颈总动脉均保持通畅,模型建立成功率为90.0%。结论犬颈总动脉囊状侧壁动脉瘤是模拟人体颅内动脉瘤的最佳模型之一。
Objective To study the availability by making experimental saccular aneurysm models of carotid arteries in canine similar to human intracranial aneurysms. Methods Twenty healthy canines with experimental saccular side-wall aneurysms of carotid arteries were created successfully by surgery. Results Forty experimental saccular side-wall aneurysms of carotid arteries were created successfully with 36 aneurysms and parent arteries maintaining patency with each other and four spontaneously occluded confirmed by angiography. Model successfurll rate reached 90% . Conclusions Experimental saccular side-wall aneurysms of carotid arteries in canines were one of best models created for simulating human intracranial aneurysms.
出处
《介入放射学杂志》
CSCD
2006年第2期85-87,共3页
Journal of Interventional Radiology
关键词
实验性动脉瘤
颈总动脉
动物模型
犬
Experimental intracranial aneurysm
Carotid artery
Animal model
