期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

急性高容量血液稀释用于全髋置换术的临床研究 被引量：2

在线阅读 下载PDF
导出
摘要 目的:采用6%中分子羟乙基淀粉(6%HES)行急性高容量血液稀释(AHHD),观察其在全髋置换术中节约用血的效力及其对凝血功能的影响。方法:22例病人分为实验组和对照组。记录两组围术期出血量、异体血输注量及补液量,分别测定稀释前、稀释后、术毕、术后第1天、术后第7天的Hb和红细胞压积(Hct)及稀释前、稀释后、术毕凝血酶原时间(PT)和活化部分凝血活酶时间(APTT)。结果:AHHD组稀释后Hb、Hct显著降低,但均在安全范围内,术后第1天和术后第7天Hct、Hb与对照组同期比较差异无显著性。AHHD组稀释后PT、APTT均明显延长,统计学上差异有显著性,但均在正常范围内。两组术中出血量差异无显著性,AHHD组11例患者均完全避免了输注异体血,对照组11例中有10例输血,平均输血量400mL,两组比较差异有显著性。结论:围术期以6%HES行AHHD可显著减少全髋置换术病人异体血输注量,对凝血功能(PT、APTT)无明显影响。
作者 张英 郑利民 魏薇 王天元
机构地区 北京大学深圳医院麻醉科
出处 《实用医学杂志》 CAS 2006年第4期402-404,共3页 The Journal of Practical Medicine
关键词 关节成形术 置换 髋 急性高容量血液稀释 6%羟乙基淀粉
分类号 R614 [医药卫生—麻醉学]
  • 相关文献

参考文献9

  • 1MIELKE L L, ENTHOIZNER E K, KLING M, et al. Preoperative acute hypervolemic hemodilution with hydroxyethylstarch: an alternative to acute normovolemic hemodilution [J]? Anesth Analg,1997,84(1): 26 -30.
  • 2SINGBARTL K, SCHLEINZER W, SINGBARTL G . Hypervolemic hemodilution : an alternative to acute normovolemic hemodilution? A mathematical analysis [J]. J Surg Res, 1999,86(2): 206-612.
  • 3KUMAR R, CHAKRABORTY I, SEHGAL R. A prospective randomized study comparing two techniques of perioperative blood conservation: isovolemic hemodilution and hypervolemic hemodilution [J]. Anesth Analg,2002,95(5): 1154 - 1161.
  • 4KUMAR A, ANEL R, BUNNELL E, et al. Effect of large volume infusion on left ventrieular volumes, performance and contractility parameters in normal volunteers [J] . Intensive Care Med, 2004, 30(7): 1361 - 1369.
  • 5MOLTER G P, SOLTESZ S, LARSEN R, et al. Haemodynamic effects following preoperative hypervolemic haemodilution with hypertonic hyperoncotic colloid solutions in coronary artery bypass graft surgery [J]. Anaesthesist,2003,52(10): 905 - 918.
  • 6LEE J G, HUDETZ A G, SMITH J J, et al. The effects of halothane and isoflurane on eerebrocortieal mieroeirculation and autorefulation as assessed by laser doppler flowmetry [J]. Anesth Analg, 1994, 79(1):58 -65.
  • 7KLAASE J M, KROON B B, VAN SLOOTEN G W, et al. Comparison between the use of whole blood versus a diluted perfusion in regional isolated perfusion by continuous monitoring of transeutaneous oxygen tension: a pilot study [J]. J Jnvest Surg, 1994,7(3):249 -258.
  • 8SEFRIN P, RAUGHS S, ZIEGLMEYER G. Changes in blood coagulation in treatment with hydroxyethyl starch [J] . Anaesthesiol Reanim , 1998, 23(6): 149 - 156.
  • 9MORTELMAS Y, MERCKX E, VAN NEROM C, et al. Effect of an equal volume replacement with 500 mL 6% hydmxyethyl starch on blood and plasm volume of healthy volunteers [J] . Eur J Anaesthesiol, 1995, 12(3): 259 - 264.

同被引文献26

  • 1盛洪广,罗振中,陈受琳,周志东,左恒,徐国海.急性高容量血液稀释对硬膜外阻滞复合全麻手术病人血液动力学的影响[J].临床麻醉学杂志,2005,21(6):430-432. 被引量：17
  • 2李真,崔建修,周国斌,赵国栋.急性超容性血液稀释用于脊柱手术的临床观察[J].实用医学杂志,2005,21(14):1561-1562. 被引量：2
  • 3秦丽文,张舟,张长椿,郑良杰.丙泊酚-异氟烷静吸复合麻醉联合急性高容量血液稀释用于颅脑手术的观察[J].实用医学杂志,2006,22(12):1393-1394. 被引量：5
  • 4Paul GB,Bruce FC,Robert KS.Clinical Anesthesia.王伟鹏,李立环主译.临床麻醉学[M],北京:人民卫生出版社,2004:294-297.
  • 5Kumar R, Chakraborty I, Sehgal R, et al, A prospective randomized study comparing two techniques of perioperative blood conservation : isovolemic hemodilution and hypervolemic hemodilution [J ]. Anesth Analg, 2002,95 (5) : 1154-1161.
  • 6Isaka M, Sakuma I, Imamura M, et al. Experimental studies on artificial blood usage for hemodilution during cardiopulmonary bypass [J]. Ann Thorac Cardiovasc Surg, 2005,11 (4):238-244.
  • 7Karkouti K, Djaiani G, Borger M A, et al. Low hematocrit during cardiopulmonary bypass associated with increased risk of perioperative stroke in cardiac surgery [J]. Ann Thorac Surg, 2005,80(4) : 1381-1387.
  • 8Sanders G, Mellor N, Richards K, et al. Prosperctive randomized controlled trial of acute normovolemic hemodilution in major gastrointestinal surgery [ J ]. Br J Anaesthesia, 2004,93 ( 6 ) : 775-781.
  • 9Creteur J, Sun Q, Abid O, et al. Normovolemic hemodilution improves oxygen extraction capabilities in endotoxic shock [J]. J Appl Physil, 2001,91 (4) : 1701 - 1707.
  • 10Hare G M, Mazer C D, Mak W, et al. Hemodilution anemia is associated with increased cerebral neuronal nitric oxide synthase gene expression [J ]. J Appl Physiol, 2003,94(5) : 2058-2067.

引证文献2

二级引证文献4

实用医学杂志
2006年 第4期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部