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白塞综合征发病的分子机制研究进展 被引量：2

An Update on Molecular Mechanism in the Pathogenesis of Behcet′s disease
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摘要 白塞综合征是免疫介导的,以血管炎为基础的多系统性疾病。目前为止,白塞综合征的确切发病机制不清,可能是在遗传背景下,感染、免疫及环境等综合因素作用的结果。Th1细胞介导的免疫反应、血管内皮细胞功能不良及自身免疫细胞凋亡异常等因素参与了白塞综合征的发病过程。 Behcet＇s disease is an immune-mediated multi-systemic vasculitis. The pathogenesis of the disease is still unclear. It may result from comprehensive action of multiple factors, including genetic and environmental factors, infections and immune abnormality. This paper is a review on the molecular mechanism in the pathogenesis of this disease.
作者 左付国 金春林 李铁男
机构地区 沈阳市第七人民医院皮肤科
出处 《国际皮肤性病学杂志》 2006年第1期35-37,共3页 International Journal of Dermatology and Venereology
关键词 白塞综合征 易感基因 免疫异常 内皮细胞 细胞凋亡 ehcet＇s disease Candidate genes Immune, abnormality Endothelial cell Apoptosis
分类号 R597 [医药卫生—内科学]
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参考文献26

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同被引文献14

  • 1杨江华,张永祥,王芳,喻荣彬,苏川,孙南雄.人外周血CD4^+ CD25^+调节性T细胞的分离、鉴定和功能特征[J].细胞与分子免疫学杂志,2006,22(2):252-254. 被引量：18
  • 2刘相东,孙善会,肖东杰,牟国营,汪运山.白细胞介素-1受体拮抗剂基因型2/2与白塞病葡萄膜炎易感性的相关研究[J].山东大学学报（医学版）,2007,45(5):467-469. 被引量：7
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国际皮肤性病学杂志
2006年 第1期

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