摘要
目的比较双氯芬酸钠栓与特拉唑嗪(高特灵)治疗前列腺痛的疗效。方法 120例前列腺痛患者,随机分为双氯芬酸钠栓组60例(双氯芬酸钠栓50 mg,经肛门直肠给药,每12小时1次,连续2周)和特拉唑嗪组60例(高特灵2 mg,口服,每12小时1次,不能耐受者改为每晚1次,连续2周)。观察对比两组疗效及副作用。结果双氯芬酸钠栓组疗效优于特拉唑嗪组,总有效率分别为97％和80％(P<0．01),显效率分别为60％和38％(P<0．05)。两组治疗后前列腺症状指数积分分别降至(2．8±2．2)分和(4．5±4．3)分(P <0．01),但是不良反应发生率分别为3％和36％(P<0．01)。结论双氯芬酸钠栓用于治疗前列腺痛疗效满意,优于特拉唑嗪。
Objective To compare the clinical efficacy of diciofenac sodium suppository and terazosin in treatment of prostatodynia. Methods 120 patients（age ranging from 19 to 48 years, mean age was 29.8 years） suffering from prostatodynia, were randomly divided into 2 groups： diclofenac sudium suppositoy group of 60 patients （50mg,rectal medication, q12h for 2 weeks） and terazosin group of 60 patients（2mg, per os, ql2h or qn for 2 weeks）. The therapeutic effects and side-effects were compared after 2 weeks treatment. Results The total clinical effective rate in diclofenac sudium suppository group was 97%, higher than that （80%） of terazosin groups（ P 〈 0.01 ）. The remarkable effective rates for each group were 60 % and 38 %, respectively （ P 〈 0.05 ）. The accumulative scores or points or prostatis symptom index taken after 2 weeks treatment decreased to （2.8 ± 2.2） and （4.5 ± 4.3 ）, respectively（ P 〈 0.01 ）. However, the occurrence rates of side-effects in each groups were 30 % and 36 % （ P 〈 0.01 ）. Conclusion The efficacy of diclofenac sudiurn suppository in treating prostatodynia is satisfactory and superior to terazosin.
出处
《中国基层医药》
CAS
2005年第11期1537-1538,共2页
Chinese Journal of Primary Medicine and Pharmacy
