摘要
目的探讨老年2型糖尿病患者糖尿病视网膜病变的患病率及相关危险因素。方法测定190例60岁及以上2型糖尿病患者糖化血红蛋白、胰岛素、C肽等各生化指标并检测眼底,根据眼底病变程度将患者分为糖尿病无视网膜病变(无病变组)、无增殖期视网膜病变(无增殖期组)及增殖期视网膜病变(增殖期组)3组,比较各组糖尿病病程及糖化血红蛋白等检测指标。结果无病变组103例,无增殖期组59例,增殖期组28例。3组糖尿病病程分别为(121.1±93.3)(、149.6±112.1)及(182.2±83.6)个月,差异有统计学意义(P<0.05);糖化血红蛋白分别为(8.7±2.3)、(9.7±2.1)及(9.5±1.8)%,差异有统计学意义(P<0.05);尿白蛋白(56.0±185.6)、(234.2±535.1)及(229.9±513.9)mg/L,(P<0.01)。Logistic回归结果显示糖尿病病程、尿白蛋白和糖化血红蛋白是糖尿病视网膜病变的独立危险因素(OR值分别为1.004、1.002和1.143)。结论在老年2型糖尿病视网膜病变患者中,糖尿病病程、尿白蛋白和糖化血红蛋白是3个独立的危险因素。
Objective To investigate the prevalence and risk factors of diabetic retinopathy （DR） in Chinese elderly diabetic patients. Methods One hundred and ninety patients with type 2 diabetic aged 60 years and over, including 93 males and 97 females were selected. The average age was 68.9 years and the average diabetic duration was 11.5 years. HbAlc, insulin, C-peptide and other clinical characteristics in all patients were tested. The retinopathy of the patients were examined by the retina-camera. Results There were 103 patients without deabetic retinopathy, 59 patients carrying non proliferative deabetic retinopathy and 28 patients carrying proliferative diabetic retinopathy. The above three groups had statistically different diabetic duration [（121.1±93.2） vs （149.6±112.1） vs （182.2＋83.5）months, P〈0.051, HbA1c [（8.7±2.3） vs （9.7±2.1） vs （9.5±1.8） %, P〈 0. 05], urine albumin [（56.0± 185.6） vs （234.2±535.1） vs （229.9± 513.9）mg/L, P〈0. 01]. Logistic regression analysis showed that diabetic duration, urine albumin and HbAlc were three independent risk factors for deabetic retinopathy（the OR values were 1. 004.1. 002,1. 143 respectively） Conclusions Diabetic duration, urine albumin and HbAlc are three independent risk factors for diabetic retinoDathv in the elderly patients with type 2 diabetic.
出处
《中华老年医学杂志》
CAS
CSCD
北大核心
2005年第12期891-893,共3页
Chinese Journal of Geriatrics
关键词
糖尿病
2型
糖尿病视网膜病变
危险因素
Diabeties mellitus, type 2
Diabetic retinopathy
Risk factors
