摘要
目的:观察不育伴精索静脉曲张(VC)患者的精液质量和精子形态学变化。方法:98例不育伴VC患者精液按WHO标准常规分析并对精子形态学进行评价。130例正常供精者精液检测结果作为对照。结果:VC患者正常形态精子和前向运动精子明显低于对照组(P<0.001),精子畸形的类型以梨形、锥形和不定型头部畸形为主。结论:VC可导致精子畸形率升高,后者可能是男性生育力受损的重要标志之一,经染色后的精子形态学分析是判定VC患者精子受损的一个敏感指标。
Objective： To examine the semen quality and the sperm morphology in infertile men with varicocele. Methods： Semen from 98 infertile men with varicocele were studied and those of 130 normal semen donors were taken as the control. Semen analysis was performed based on the methods described in the WHO manual and sperm morphology was evaluated by WHO criteria. Results： A significantly reduced percentage of normal morphologic sperm and of forward progression were found in patients with varicocele comparing with those of the control（ P 〈 0. 001 ）. The head defects were observed as the predominant type of sperm malformation. Conclusion ： The varicocele increases malformed sperm in ejaculates, which may result from impaired male fertility by varicocele. Sperm morphologic assessment with WHO criteria provides a sensitive and practical measurement of sperm damage in infertile men with varicocele. Natl J Androl,2005 ,11 （ 12 ） ：933-935
出处
《中华男科学杂志》
CAS
CSCD
2005年第12期933-935,共3页
National Journal of Andrology
