摘要
骨质疏松合并骨折是一种常见而严重的疾患,本文总结了治疗方面的近期进展和新概念。骨折后由于制动治疗导致继发性骨质疏松,在原发性骨质疏松的基础上,骨丢失愈发严重,形成恶性循环,影响愈合。因此,治疗的关键是要阻断这一恶性循环,防止或减少骨丢失。尽早进行功能练习和负重活动,常规服用治疗骨质疏松的药物,两者是同等重要的。牢靠的内固定和假体置换应该是多数骨折治疗的首选方法。在药物治疗方面,降钙素、激素替代疗法(利维爱等)、双磷酸盐(福善美等)、维生素D2、维生素D3及钙剂都是适用的。
Osteoporosis complicated with fracture is a common and severe condition. This paper summarizes present advances and new concepts in its treatment. Since the secondary osteoporosis will likely develop after fracture treatment with immobilization, more and more bone mass will get lost in addition to primary osteoporosis. A vicious cycle will be established and influence the fracture healing. Therefore, the key to the treatment is to block the vicious cycle to stop or decrease the bone loss. As a routine measure, to do exercises and weight-bearing activities as early as possible is as important as to take medicines for osteoporosis treatment. Stable internal fixation and prosthetic replacement should be firstly chosen for treatment of most fractures. In drug treatment, calcitonin, bisphosphonate （alendronate）, HRT （Livial）, vitamins D2 and D3, and calcium are indicated.
出处
《中华创伤骨科杂志》
CAS
CSCD
2005年第12期1101-1103,共3页
Chinese Journal of Orthopaedic Trauma
关键词
骨质疏松
骨折
治疗
Osteoporosis
Fracture
Treatment
