摘要
目的利用计算机三维治疗计划系统创建125I粒子平面植入条件下剂量分布特征与等剂量分布曲线。方法利用计算机治疗计划系统创建125I粒子三角形分布、正方形分布、六边形分布、十二边形分布时剂量特征,求出1 000、3 000、6 000、9 000、12 000、15 000和20 000 cGy剂量分布曲线。计算距离平面插植中心点距离0、0.5、1.0、1.5、2.0、2.5、3.0和4.0cm处剂量分布。结果利用三维粒子治疗计划系统可以模拟出平面插值条件下等剂量曲线分布。在三角形、正方形、五边形、六边形条件下,粒子距离中心超出2.0 cm、2.5 cm、3.0 cm、4.0 cm时,中心剂量低于10 Gy,需要增加粒子,提高中心剂量。结论利用计算机三维治疗计划系统可以模拟平面条件下不同几何形状125I粒子种植分布的等剂量曲线分布,求出距离中心点不同部位的剂量,对临床具有十分重要的指导意义。
Objective To establish the isodose curves and dose calculation models of ^125I seed plane implantation using the three -dimensional treatment planning system （3D -TPS）. Methods The isodose cures of 1 000 cGy, 3 000 cGy, 6 000 cGy, 9 000 cGy, 12 000 cGy, 15 000 cGy, and 20 000 cGy and dose calculation models of triangular, quadrilateral, hexagon, and dodecagon patterns of ^125 I seed plane implantation were created using the 3D - TPS. The isocenter dose pattern of 0, 0.5, 1.0, 1.5, 2.0, 2.5, 3.0, and 4.0 cm from the plane center was calculated with 3D - CRT. Results The study showed that if doses were less than 10 Gy at 2.0 cm, 2.5 cm, 3.0 cm and 4.0 cm apart from the center of triangular, quadrilateral, hexagon, and dodecagon patterns and the distance was beyond 1 cm between seeds, there was a low dose region in the centeral point. Conclusions The study showed that the isodose distribution curves and dose calculation models in plane implantation were primarily established using the seed implantation 3D -TPS.
出处
《中国微创外科杂志》
CSCD
2005年第12期1061-1062,共2页
Chinese Journal of Minimally Invasive Surgery
关键词
^125Ⅰ
平面插植
布源分布
^125I seed
Plane implantation
Isodose distribution
