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量子点—人表皮生长因子纳米荧光探针的制备及其对卵巢癌细胞SKOV-3的识别 被引量:2

Preparing of Quantum Dots-EGF Nanoscale Fluorescent probes and Their Specific Recognizing Ovarian Cancer Cells SKOV-3
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摘要 在连接试剂1-乙基-3(3-二甲基胺基丙基)碳二亚胺盐酸盐(1-ethyl-3(3-dimethylaminopropyl)-carbodiimide,EDC)的作用下,将水相合成的量子点(Quantumdots,QDs)与人表皮生长因子(Epidermal growth factor,EGF)进行了连接,通过毛细管电泳、吸收光谱以及荧光光谱对连接前后的QDs进行了表征,获得的QDs-EGF可识别卵巢癌细胞SKOV-3。 Water- soluble quantum dots (QDs) have been Successfully conjugated with epidermal growth factor (EGF) using 1- ethyl- 3(3- dimethylamino propyl).-carbodiimide (EDC) as a cross- linking reagent. The properties of the QDs and QDs - EGF conjugates were characterized by capillary electrophoresis (CE), UV - Vis absorption and photoluminescent (PL) spectra. The QDs - EGF conjugates obtained could recognize the ovarian cancer cells SKOV - 3.
出处 《上海生物医学工程》 CAS 2005年第4期201-204,共4页 Shanghai Journal of Biomedical Engineering
基金 国家自然科学基金(批准号:30300085) 上海市纳米专项(批准号:0352nml10)资助项目的部分内容。
关键词 量子点-人表皮生长因子 纳米荧光探针 制备方法 卵巢癌 SKOV-3细胞 Quantum dots Epidermal growth :factor Capillary electrophoresis Optical properties Ovarian tumor cells Recognition
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