摘要
在连接试剂1-乙基-3(3-二甲基胺基丙基)碳二亚胺盐酸盐(1-ethyl-3(3-dimethylaminopropyl)-carbodiimide,EDC)的作用下,将水相合成的量子点(Quantumdots,QDs)与人表皮生长因子(Epidermal growth factor,EGF)进行了连接,通过毛细管电泳、吸收光谱以及荧光光谱对连接前后的QDs进行了表征,获得的QDs-EGF可识别卵巢癌细胞SKOV-3。
Water- soluble quantum dots (QDs) have been Successfully conjugated with epidermal growth factor (EGF) using 1- ethyl- 3(3- dimethylamino propyl).-carbodiimide (EDC) as a cross- linking reagent. The properties of the QDs and QDs - EGF conjugates were characterized by capillary electrophoresis (CE), UV - Vis absorption and photoluminescent (PL) spectra. The QDs - EGF conjugates obtained could recognize the ovarian cancer cells SKOV - 3.
出处
《上海生物医学工程》
CAS
2005年第4期201-204,共4页
Shanghai Journal of Biomedical Engineering
基金
国家自然科学基金(批准号:30300085)
上海市纳米专项(批准号:0352nml10)资助项目的部分内容。