摘要
用ND(新城疫)Ⅰ系疫苗大剂量肌肉注射2周龄雏鸡的方法建立实验性免疫应激模型,检测胸腺中CD4+、CD8+T细胞动态变化以及超微结构变化.结果显示:免疫应激前期(1-5d)表现为CD4+T细胞数目减少,CD8+T细胞数目增加的趋势;部分T细胞发生凋亡,并且是一个逐渐加剧的过程,呈现从凋亡到坏死的病理学变化过程.
In order to build the model of experimental immunologic stress, 200 two-week-old chickens were vaccinated with amounts of Newcastle Disease I Series by intramuscular injection. After immunologic stress ,The number of the CD4 ＋ T cell began to decrease ,but the number of the CD8 ＋ began to increase; the part of T cell of thymus came with apoptotic. , continually, The pathological changes of T cell took on Putrescence.
出处
《山西师范大学学报（自然科学版）》
2005年第4期78-82,共5页
Journal of Shanxi Normal University(Natural Science Edition)
基金
山西师范大学2004年校基金项目
关键词
胸腺
T细胞
免疫应激
Thymus
T cell
Immunologic stress
