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4899例结节性甲状腺肿的临床分析 被引量:26

Analysis of 4 899 cases of nodular goiter
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摘要 目的:分析过去13年间在我院外科诊治的哈尔滨及其周围地区结节性甲状腺肿(nodular goiter,NG)的 临床特点及外科治疗经验。方法:回顾性分析我院外科手术治疗4899例结节性甲状腺肿的临床资料。结果:该组病 例的男女比例为1∶5. 3;发病年龄为3~83岁,平均45. 2岁;双侧病变4158例(84. 9%);单侧病变741例(15. 1%),其 中右叶481例(9. 8%),左叶260例(5. 3%);结节性甲状腺肿合并甲亢者304例(6. 2%);因复发结节性甲状腺肿再次 手术者220例(4. 5%)。4899例中行甲状腺大部切除术4118例(84%),甲状腺次全切除和近全切除术477例 (9. 7%),甲状腺部分切除加结节切除304例(6. 2%)。结论:NG 的发病以双侧为多,单侧病变中以有叶居多;尽管甲状 腺大部切除术仍为目前外科治疗结节性甲状腺肿的主要术式,但是鉴于其高复发率,治疗结节性甲状腺肿的术式有 待进一步讨论。 Objective To clinically review and analyze a large consecutive series of nodular goiter cases surgically treated in our hospital during last 13 years and they were inhabitants of Harbin or its surrounding area. Methods A total of 4 899 consecutive cases of nodular goiter were treated in our division, and were retrospectively reviewed. Results In the series, M:F was 1:5.3. Age of the patients: 3 to 83 yrs with an average of 45.2 yrs. The lesions involved bilateral lobes in 4 158 cases (84.9%) and unilateral lobes in 741 cases (15.1%) with 481 (9.8%) cases involving the right lobe and 260 (5.3%) cases involving the left lobe. Three hundred and four cases (6.2%) were complicated with hyperthyroidism (toxic goiters); 220 cases (4.5%) occurring as recurrent nodular goiters. Extent of resection: there were 4 118 cases (84%) of partial thyroidectomy; 477 cases (9.7%) of subtotal thyroidectomy/near total thyroidectomy; there were 304 cases (6.2%) of nodule(s) resection. Conclusions In nodular goiter, more cases are bilaterally involved; and in unilateral cases, the right lobes are more involved than the left. Although major thyroidectomy is currently the surgical intervention of choice for nodular goiter, other alternatives should be considered due to its high rate of recurrence.
作者 陈序吾 陈磊
出处 《外科理论与实践》 2005年第6期519-521,524,共4页 Journal of Surgery Concepts & Practice
关键词 甲状腺肿 结节性 甲状腺功能亢进症 复发 甲状腺切除术 Nodular goiter Hyperthyroidism Recurrence Thyroidectomy
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