摘要
目的 探讨结晶天花粉蛋白注射液宫腔注射联合米非司酮治疗未破裂异位妊娠的临床效果。方法 对58例未 破裂异位妊娠患者随机分为两组,治疗组和对照组,治疗组:30例采用结晶天花粉蛋白注射液宫腔注射,米非司酮50mg,2/d, 口服,连服3d。对照组:氨甲蝶呤(MTX),25mg,1/隔日,肌注,共5次。定时监测血、尿HCG、B超,比较两组治疗效果及尿HCG 转阴天数。结果 两组间有效率无显著统计学差异(P>0．05),两组尿HCG转阴的平均天数有显著性差异(p<0．01),治疗 组明显缩短。结论 结晶天花粉注射宫腔注射联合米非司酮治疗异位妊娠,疗效好、无明显副作用,可作为保守异位妊娠的 首选治疗方案。
Objective： To study the curative effect of unruptured ectopic pregnancies by intrauterine injection of Radix trichosanthis and peroral Mifepristone. Methods： 58 cases of unruptured ectopic pergancies were derided into two groups at random ： treating group and controlled group, 30 cases of treating group were treated by intrauterine injection of crystalline Radix Trichosanthis and peroral Mifepristone （50mg, orally 2 times daily, total three days）, and MTX, 25mg, intramuseluarly, once every days, total five times, in 28 cases of controlled group. The serum and urine hmnan chorlonic gonadotropin （HCG） levels and B ultrasound were monitored periodically. Results：There was no statistically significant difference in curative ratio and marked difference in days of urine HCG converted into negative between the two groups. There was less days in treating group than controlled group. Conclusion： It had good cure effect and no significant side - action to treat unruptured actopic preg- nancy by intrauterine injection of Radix trichosanthis and peroral Mifepristone, may be the first choice to treat unruptured ectopic pregnancies as conservative therapy.
出处
《中国优生与遗传杂志》
2005年第11期84-85,共2页
Chinese Journal of Birth Health & Heredity
关键词
异位妊娠
天花粉
米非司酮
Ectopic pregnancy
Radix trichosanthis
Mifepristone
