摘要
目的:定量观察纳米羟基磷灰石复合胶原材料(nHAC)在骨膜下的成骨高度及可吸收速度,为其应用于萎缩牙槽嵴加高术提供可靠的数据依据。方法:免颅骨骨膜下埋植nHAC于不同时间点取材,常规标本制作后,用显微测微尺C5型网格,采用“数点法”测量各时间点标本中新骨形成的高度及材料的剩余量,并和羟基磷灰石(HA)组对比。结果:术后12周时nHAC组新骨形成的高度为2.63mm,材料剩余量占原植入材料的53.2%,被吸收的材料量占46.8%。结论:nHAC在骨膜下引导新骨生成的同时可以被吸收。
Objective ：To study the bone-conductivity and absorbability of nano-hydroxyapatite/collagen （nHAC） composite implanted under the calvarial periosteum in rabbits. Methods：24 nHAC samples and 24 HA samples were prepaired in the shape of round disk with the diameter of 8 mm and thickness of 3 mm. nHAC samples were implanted under ealvarial periosteum on the left side and HA samples on the right of 24 rabbits. The bone-conductivity and absorbability of the samples were examined hy new hone height measuring and residual implant materia measuring 2, 4,8 and 12 weeks after operation. Results：2,4,8 and 12 weeks after implantation new bone height（ram） in nHAC group was 0.54±.009,0.72±＋0. 12, 1.83±0.14 and 2.63±0.07, that in HA group 0. 13 ± 0.11 ,0.31± 0.12, 1.23±0.05 and 1.75±. 14,respectively（P〈0.01）;the ratio（%） of residual nHAC was 95.2±0.7,77.8±0.6,61.3 ±0.1 and 53.2±0.3,that of HA 99.3±0.5,96.1±0.7,93.3±0.5 and 91.4±0.9,respectively（P 〈 0.05 or P 〈 0.01 ）. Conclusion：Bone conductivity and absobability of nHAC are greater than those of HA.
出处
《实用口腔医学杂志》
CAS
CSCD
北大核心
2005年第6期835-837,共3页
Journal of Practical Stomatology
基金
国家"973"基金项目资助(G1999054308)
