摘要
目的:探讨大肠腺瘤性息肉的癌变特征。方法:对6144例因有下消化道症状患者行结肠镜检查,记录大肠息肉患者的临床表现以及年龄、性别等资料,对大肠腺瘤性息肉的发生率、内镜下表现、病理类型进行分析。结果:1)结肠腺瘤性息肉占息肉患者总数的41.72%,男性占55.34%,女性占44.66%;年龄>60岁患者占69.72%。临床症状中便血占66.28%。分布于左半结肠患者显著多于右半结肠患者(P<0.001);2)重度不典型增生和癌变息肉直径>2cm者占79.73%,分布于左半结肠患者也显著多于右半结肠患者(P<0.0001)。重度不典型增生和癌变率在腺瘤性息肉显著高于炎性息肉(P<0.001);且在三种腺瘤性息肉间存在显著差异(P<0.001)。结论:结肠镜检查大肠腺瘤性息肉的检出率较高,临床症状以便血最多。其中重度不典型增生和癌变息肉具有一定的结肠镜下特征表现并且和息肉的病理类型密切相关。
To review the clinical manifestations of colorectal polyps and to analyze the feature of malignant transformation. Methods： Colonoscopy was performed in 6144 individuals who had lower bowel symptoms, The information included the data of sex and age, and the clinical symptoms were recorded for patients with colorectal polyps. The incidence, colonoscopy findings and histopathologieal lesion of colorectal polyps were analyzed. Results： a） 30.66% of the cases were identified to have eolorectal polyp, among which, 41.72% cases were adenomatous phenotype （with 55.34% male and 44.66% female）, and 69.72% cases were from individuals over 60 years. Gastrointestinal bleeding occurred in 66.28% of the cases. The incidence rate on left colon was more than on the right colon. （P〈0.001）. b）. 79.73% of the cases were the gravis atypical hyperplasia and cancerous polyps with more than 2.0 cm in diameter. The incidence rate on left colon was more than on the right colon. There was a significant difference between the incidence in gravis hypereplasia and cancerous polyps than in inflammatory polyps, for the three adenomatous polyps there were very significant differences （P〈0.001）. Conclusions： A high incidence rate of adenomatous polyps is found in colonoscopy. Gastrointes- tinal bleeding is a major symptom of colorectal polyps. The gravis atypical hyperplasia and cancerous polyps have the feature of colonoscopy and they relate to the histopathology.
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
2005年第22期1290-1292,共3页
Chinese Journal of Clinical Oncology
