摘要
目的调查了解儿童、妇女铁减少(ID)、缺铁性贫血(IDA)及铁缺乏症(IDD)患病率。方法随机抽取汉中市城区7月～7岁儿童532名,30岁以下妊娠38周以内孕妇203名,30岁以下未孕育龄妇女200名为调查对象。检测了血红蛋白(Hb)、锌原卟啉(ZPP)、血清铁蛋白(SF)等指标。结果7个月～7岁儿童ID平均43.80%,IDA平均9.96%。其中7个月～12个月婴儿ID71.67%,IDA22.50%;3个月～36个月幼儿ID33.13%,IDA8.13%;37个月～7岁儿童ID37.30%,IDA5.16%。孕妇ID平均82.17%,IDA平均37.93%。其中早孕组ID75.91%,IDA14.46%,中孕组ID77.14%,IDA51.43%;晚孕组ID100.00%,IDA58.00%。未孕育龄妇女ID49.50%,IDA25.00%。儿童ID、IDA不同年龄组有显著差异(P<0.01),即年龄越小、患病率越高。孕妇孕龄组之间有显著性差异(P<0.01)。即孕龄越大,患病率越高。孕妇ID、IDA患病率与育龄妇女有显著性差异(P<0.01)。孕妇患病率明显高于育龄妇女。不同年龄组儿童、不同孕期孕妇及育龄妇女ID患病率均大于IDA患病率。结论本市儿童、孕妇、育龄妇女铁缺乏症比较普遍,ID、IDA患病率均高于国外和全国平均水平。隐性缺铁十分严重,已成为营养性铁缺乏症的主要问题。婴幼儿和晚期孕妇是铁缺乏症高发人群。
Objective To collect epidemiological data of iron deficiency in Hanzhong children and women, so more rational strategies of prevention and treatment against iron deficiency can be made. Methods The children 7 month to 7 years of age and the women before the age of 30 years in Hanzhong were randomly selected. Ultimately, 532 children, 203 gravidas within 38 weeks pregnancy and the 200 child - bearing age women who weren＇t pregnant were selected as study subjects. Hemoglobin （Hb） was measured by cyanmethmoglobin assay, zinc protoporphorin by hemofluorescence assay and serum ferritin by radioimmunoasssay. Results The prevalence rates of iron depletion （ID） and iron deficiency anemia （IDA） were 43.80% and 9.96% respectively in children 7 months to 7 years in Hanzhong city. The prevalence rates were highest in infants （ID 71.67%, IDA 22.50%）, followed by toddlers aged 1 -3 years （ID 33.13%,IDA 8.13%） and preschoolers aged 4 to 7 years （ID 37.30%, IDA 5.16% ）. The prevalence rates of iron depletion （ID） and iron deficiency anemia （IDA） were 82.17% and 37.93% respectively in gravidas. The prevalence rates were highest in late pregnancy group （ID 100%, IDA 58.00%） followed by the medium- term pregnancy group （ID 77.14%, IDA 51.43%） and the early pregnancy group （ID 75.91%, IDA 14.46%）. The prevalence rates of iron depletion （ID） and iron deficiency anemia （IDA） were 49.50% and 25.00% in the child - bearing age women who weren＇ t pregnant. These datas showed that there were statistically significant differences （P 〈0.01） in respectively aged children. That is to say, the prevalence rates of the young children are higher than that of the elder. At the same time, there were statistically significant differences （P 〈 0.01 ） in different period of pregnancy. That is, the prevalence rates of the later pregnancy were higher than that of the early pregnancy. The ID and IDA prevalence rates of gravidas were obviously different from the child - bearing age women（P 〈 0.01 ）. Namely the prevalence rates of gravidas were significantly higher than that of the child- bearing age women. So the ID prevalence rates of different age group children, different period gravidas and child- bearing age women were higher than the IDA. Conclusion The iron deficiency of children, gravidas and child- bearing age women in Hanzhong are widespread. The ID and IDA prevalence rates are higher than the average level of abroad and the other cities in our country. The latent iron deficiency is the main prolem of nutritional iron deficiency. The present study also illustrated that infants and the women of later prenancy are at higher risk for iron deficiency.
出处
《中国小儿血液》
2005年第4期153-156,共4页
China Child Blood
