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神经反应映射阈值和电诱发镫骨肌反射阈值与舒适阈的比较

Comparison NRI thresholds and EARTs with M-Levels
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摘要 目的比较使用较高刺激速率的高分辨率(HiResolution,HiRes)言语编码方式测得的舒适阈(most comfortable levels,M-Levels)与使用较低刺激速率测得的电诱发镫骨肌反射阈值(electrical lyevoked auditory reflex thresholds,EARTs)和神经反应映射(neural response imaging,NRI)阈值。方法对象为9例使用美国Clarion CII人工耳蜗系统的极重度耳聋患者,年龄为6至29岁。应用SoundWave编程软件,使用双相脉冲记录NRI反应波形。刺激电极为奇数电极。记录每一刺激电极的软件分析NRI阈值(tNRI)和人工分析NRI阈值(1stNRI)。测试EARTs时,使用短言语声(speech bursts)同时刺激4个相邻电极,由阻抗桥(impedance bridge)记录镫骨肌反射。结果M-Levels与tNRI的相关系数r=0.675(P=0.000),与1stNRI的相关系数为r=0.741(P=0.000)。M-Levels均值较1stNRI低20CU(clinical unit,临床单位),较tNRI高12CU。各电极M-Level曲线走行与tNRI及1stNRI曲线走行相似。EARTs与M-Levels的相关系数为r=0.710(P=0.000)。EARTs均值较M-Levels高14CU。结论使用HiRes进行测试,1stNRI与M-Levels的相关性较tNRI高,EARTs与M-Levels的相关性较tNRI高,较1stNRI低。对于术后调试不能准确判断响度大小的小龄儿童患者,NRI是一个有效的客观测试方法。 OBJECTIVE The purpose of this study is to find out how HiResolution sound processing,designed to deliver high-rate stimuli,will relate to electrically evoked auditory reflex thresholds (EART) and electrically evoked compound action potential (ECAP) measurements produced by low-rate stimuli. METHODS Nine profoundly hearing-impaired children and adults between 6 to 29 years old participated in the study. Neural response imaging (NRI) responses were elicited using pulse trains consisting of biphasic pulses by using the SoundWave programming software. Stimuli were delivered to the odd electrodes, tNRI and 1^stNRI were recorded for each stimulating electrode. The“speech bursts”stimuli used in EARTs recording is delivered to 4 electrodes at a time,Stapedial reflexes were recorded from the impedance bridge. RESULTS The correlation between tNRI and (M-Levels) most comfortahle levelsis r=0.675(P=0.000) from eight patients and 53 stimulating electrodes. The correlation between 1^stNRI and M-Levels is r=0.741(P=0.000)from eight patients and 53 stimulating electrodes. The M-Levels value on average is 20 CU lower than the 1^stNRI value and 12 CU higher than the tNRI value. The M-Level pattems across the electrode arrayoveraJI were similar to the tNRI or 1^stNRI patterns. The correlation between EARTs and M-Levels is r=0.710(P=0.000)from seven patients and 112 stimulating electrodes. The EARTs value on average is 14 CU higher than the M-Levels value. CONCLUSION 1^stNRI has better correlation with HiResolution M-Levels than tNRI. Comparing with tNRI and 1^stNRI,the EARTs have higher correlation with HiResolution M-Levels than tNRI and lower correlation with 1^stNRI. NRI is a useful method for programming young children who cannot demonstrate reliable loudness judgment.
出处 《中国耳鼻咽喉头颈外科》 北大核心 2005年第9期569-572,共4页 Chinese Archives of Otolaryngology-Head and Neck Surgery
关键词 耳蜗植入物 治疗 计算机辅助 电诱发镫骨肌反射 神经反应 舒适阈 阈值 映射 刺激电极 Deafness Cochlear Implants Therapy,Computer-Assisted
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参考文献6

  • 1Brown C J, Hughes ML, Luk B, et al. The relationship between EAP and EABR thresholds and levels used to program the nucleus 24 speech processor: data from adults. Ear Hear,2000, 21:151-163.
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  • 5陈雪清,韩德民,赵啸天,王硕,孔颖,刘莎,莫玲燕,刘博,吴燕君.人工耳蜗植入术后神经反应遥测阈值与行为阈值及舒适阈的比较[J].中华耳鼻咽喉科杂志,2002,37(6):435-439. 被引量:18
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二级参考文献5

  • 1Cullington H.Preliminary neural response telemetry results[].British Journal of Audiology.2000
  • 2Lai WK,Dillier N.A simple two-component model of the electrically evoked compound action potential in the human cochlear[].Audiol Neurootol.2000
  • 3Hughes ML,Brown CJ,Abbas PJ,et al.Comparison of EAP thresholds with MAP levels in the nucleus 24 cochlear implant:data from children[].Ear and Hearing.2000
  • 4Brown CJ,Hughes ML,Luk B,et al.The relationship between EAP and EABR thresholds and levels used to program the nucleus 24 speech processor: data from adults[].Ear and Hearing.2000
  • 5Shallop JK.Facer GW, Peterson A.Neural response telemetry with the nucleus CI24M cochlear implant[].Laryngoscope.1999

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