摘要
目的探讨原位肝移植(OLT)术后肺部感染的特点和易感因素。方法回顾性总结128例原位肝移植的临床资料,分析肺部感染的主要致病菌、感染发生的时间及易感因素。结果128例患者OLT术后共发生肺部感染48例(37.5%),其中27例(56.3%)发生在术后7d内,34例(70.8%)为混合感染;死亡6例(12.5%),其余治愈。致病菌前几位依次为铜绿假单胞菌,鲍曼/溶血不动杆菌、金黄色葡萄球菌和曲霉菌。结论多种病菌可致肝移植术后肺部感染,并与受者的体质、机械通气及免疫抑制剂应用等诸多因素有关。
Objective To investigate the characteristics of pulmonary infection and susceptible factors following orthotopic liver transplantation （OLT）. Methods Clinical data of 128 patients who underwent OLT from Feb. 1999 to Dec. 2004 were studied retrospectively in order to analyze primary pathogens, infectious time and susceptible factors. Results Forty-eight （37. 5 %） of 128 patients had pulmonary infections and 27 （56.3 %） of them developed within postoperative 7 days. Thirty-four （70. 8 %） cases suffered from mixed infection and 6 （12.5 %） died in the hospital after OLT. The primary pathogenic germs included Pseudomonas aeruginosa, Acinetobacter baumannii/haenolyticus, Golden staphylococcus, Aspergilosis and so on. Conclusion Pulmonary infection can be caused by various pathogens and associated with patients＇ constitution, mechanical ventilation, immunosuppressive drugs and so on.
出处
《中华器官移植杂志》
CAS
CSCD
北大核心
2005年第10期584-586,共3页
Chinese Journal of Organ Transplantation
