摘要
目的:探讨无创机械通气在COPD合并早期II型呼吸衰竭救治中的价值。方法:收集我院66例COPD合并早期Ⅱ型呼吸衰竭患者临床资料,分为药物组(42例)与经鼻/面罩双水平气道正压通气(BiPAP)组(24例),χ2与t检验分析各种相关因素对治疗效果和预后的影响。结果:药物组与BiPAP组比较,两组治疗前年龄、意识障碍程度、动脉血气分析差别无显著性(P>0.05),两组平均住院天数差别无显著性(P>0.05),两组治疗后7天PaO2较治疗前明显升高(P<0.01),PaCO2较治疗前明显降低(P<0.01),但BiPAP组较药物组更为显著(P<0.01)。BiPAP组气管插管发生率明显少于药物组(P<0.05),死亡率少于药物组(P<0.05)。结论:无创机械通气是救治COPD合并早期II型呼吸衰竭患者的有效方法。
Objective： To evaluate effects of mechanical non-invasive ventilation on rescue for patients with chronic obstructive pulmonary disease （COPD） （type Ⅱ respiratory failure early）. Methods： Clinical data of 66 patients with COPD with type Ⅱ respiratory failure were reviewed. We designed 24 cases in the BiPAP group and 42 cases in the drug group. Related factors that affect their outcome and prognosis were statistically analyzed using χ^2 and t test. Results： There was no significant difference on respect to age, unconsciousness, and level of blood gas between two groups before therapy （P〈0. 05）. After day 7 treatment, level of PaO2 in BiPAP group was significantly higher than that of the drug group （P〈0. 01）; in contrast on the level of PaCO2 （P〈0. 01）. The rates of intubations and hospital mortality in BiPAP group was significant lower than that of the drug group （P〈0. 05 ）. The days of hospitalization were similar in the two groups（P〉0. 05）. Conclusions： Mechanical non-invasive ventilation is one of the most effective measures in treating patients with COPD with type II respiratory failure early at emergency.
出处
《青海医药杂志》
2005年第8期11-13,共3页
Qinghai Medical Journal
关键词
无创机械通气
Ⅱ型呼吸衰竭
慢性阻塞性肺部疾病
Mechanical non-invasive ventilation
Chronic obstructive pulmonary disease
Respiratory failure
