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以负重游泳动物试验评价抗疲劳作用的影响因素分析 被引量:18

Analysis of Factors Affecting the Loaded Swimming in Mice
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摘要 根据卫生部《保健食品的功能学评价程序和检验方法》中抗疲劳检验方法,通过单因素试验和L8(27)正交试验研究了对受试小鼠游泳时间的影响因素。实验结果发现:负重游泳时间影响因素的主次水平为:游泳水温>受试时间>游泳水温与受试时间的交互作用>饲养温度>受试时间与饲养温度的交互作用;且当受试时间为30d,游泳水温为25℃,饲养温度为25℃时,复方中药功能液Ⅰ的负重游泳时间最显著。 Basing on the basic project defined in Functional Assessment Procedure and Test Methods of Health Food, which was issued by Chinese Sanitary Department, some factors such as the feeding temperature, water temperature of swimming experiment and experiment time would impact the time of loading swimming of mice. The method combined orthogonal test L8(2^7) has been applied to research the effecting factors of experiment time, water temperature of swimming experiment, feeding temperature and their mutual action in loaded swimming of china medicine function liquid I , the orders of effecting factors of loading swimming applied by extreme difference (R low) was: Water temperature of swimming experiment 〉 experiment time 〉 (water temperature of swimming experiment × experiment time) 〉 feeding temperature 〉 (experiment time × feeding temperature). The best combination in the experiment of loaded swimming of china medicine function liquid I was: the test lasted for 30d, the water temperature of swimming experiment was 25 ℃ and the feeding temperature was 25 ℃. Therefore, the accuracy of loaded swimming experiment should be increased, or it would result in contingency of anti-fatigue appraisal results and unavoidably cause the phenomenon of bad reappearance.
出处 《食品科学》 EI CAS CSCD 北大核心 2005年第8期399-403,共5页 Food Science
关键词 动物试验 抗疲劳 影响因素 分析 animal experiment anti-fatigue effecting factors analysis
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