摘要
采用GC-FID,采用内标法测定了3,4-二甲氧基苯乙腈含量,外标法测定了杂质邻苯二酚、藜芦醇含量,对3,4-二甲氧基苯乙腈、邻苯二酚和藜芦醇的色谱分离条件进行了优化。3,4-二甲氧基苯乙腈的添加平均回收率为99.8%～100.1%,RSD 0.96%,准确度和精密度均能满足常量分析的要求;邻苯二酚和藜芦醇的检出限分别为100 mg/kg和50 mg/kg。
An internal standard method were studied for quantitative analysis of 3,4-dimethoxy phenyl acetonitrile by GC-FID,and an external standard method for quantitatively determinate the impurities pyrocatechol and veratryl alcohol.The average recovery of 3,4-dimethoxy phenyl acetonitrile was 99.8～100.1%,and RSD was 0.96%.The accuracy and precision could meet the requirements of constant analysis.The chromatographic conditions of 3,4-dimethoxy phenyl acetonitrile,pyrocatechol and veratryl alcohol were defined.The...
出处
《精细化工中间体》
CAS
2010年第6期67-69,共3页
Fine Chemical Intermediates
关键词
3
4-二甲氧基苯乙腈
GC-FID
邻苯二酚
藜芦醇
内标法
外标法
3
4-dimethoxy phenyl acetonitrile
GC-FID
pyrocatechol
veratryl alcohol
internal standard method
external standard method
