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肝脏局灶性结节性增生60例临床分析 被引量:34

Focal nodular hyperplasia of the liver: a report of 60 cases
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摘要 目的探讨肝脏局灶性结节性增生的诊断和治疗,提高对肝脏局灶性结节性增生(focal nodular hyperplasia oftheliver,FNH)的认识.方法回顾性分析60例FNH的临床表现、影像学表现、病理学检查及外科治疗.结果我院1993-2003年共收治经病理证实的FNH 60例,共72个病灶.男性41例,女性19例,平均年龄37岁.单发者55例,多发者5例.肿瘤直径小于5 cm50例,5~10 cm 9例,大于10 cm 1例.术前确诊率55.0%(33/60),其中彩超确诊率33.3%(19/57),CT58.3%(28/48),MRI 72.0%(18/25).60例均获手术切除,术后恢复良好,无复发.结论 CT和MRI是FNH的重要诊断方法,但部分典型FNH及所有的非典型FNH术前很难做出明确诊断.对有临床症状或诊断不明确的病例应行手术切除. Objective To evaluate the diagnosis and treatment of focal nodular hyperplasia of the liver (FNH). Methods Retrospective analysis was made on 60 FNH cases in terms of clinical findings, images, pathologic examination and surgical treatment. Results Of the 60 FNH patients in our hospital from 1993 to 2003, 41 were male and 19 female. The average age was 37 year's old. Fifty-five cases had single focus, the other five were of multiple lesion, with tumor diameter 〈5 cm in 50 cases, 5 - 10 cm in 9 cases, and 〉 10 cm in one. Correct preoperative diagnosis was made in 33 cases (55%). The correct diagnostic rate of BUS, CT and MRI was 33.3%, 58.3% and 72.0%, respectively. All 60 cases underwent operation with an uneventful recovery and without recurrence at follow-up. Conclusions CT and MRI are mandatory for the diagnosis of FNH. Definite preoperative diagnosis is usually difficult even in cases of typical type of FNH. Surgical resection is the treatment of choice when a patient becomes symptomatic or when malignancy could not be excluded.
出处 《中华普通外科杂志》 CSCD 北大核心 2005年第7期397-399,共3页 Chinese Journal of General Surgery
关键词 肝脏 局灶性 结节性增生 FNH 肝细胞 静脉血流 Liver neoplasms Focal nodular hyperplasia Diagnosis Treatment
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  • 1Di Carlo I, Urrico GS, Ursino V, et al. Simultaneous occurrence of adenoma, focal nodular hyperplasia, and hemangioma of the liver:are they derived from a common origin? J Gastroenterol Hepatol,2003, 18:227-230.
  • 2Becker YT, Raiford DS, Webb L, et al. Rupture and hemorrhage of hepatic focal nodular hyperplasia. Am Surg, 1995, 61:210-214.
  • 3Nguyen BN, Flejou JF, Terris B, et al. Focal nodular hyperplasia of the liver: a comprehensive pathologic study of 305 lesions and recognition of new histologic forms. Am J Surg Pathol, 1999, 23:1441-1454.
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