摘要
水痘是由水痘-带状疱疹病毒(VZV)引起的儿童期高度传染性疾病。世界各地都有发生。VZV初次感染后可在体内建立潜伏感染,以后可被激活引起带状疱疹。1974年研制成功的水痘减毒活疫苗对预防和控制水痘有着重要作用。该文介绍了水痘疫苗的由来、安全性、免疫效果和免疫策略等。
Chickenpox is a highly contagious childhood infection caused by varicella zoster virus(VZV). It occurs worldwide.After primary infection,VZV remains latent in dorsal route ganglia and is reactivated later in life, leading to herpes zoster. A live attenuated varicella vaccine (Oka strain), developed in 1974,played an important role in prevention and control of varicella.This review will cover origin, safety, efficacy, and immunization strategies of the varicella vaccine.
出处
《中国计划免疫》
2005年第3期238-242,共5页
Chinese Journal of Vaccines and Immunization
