摘要
用流式细胞仪（ＦＣＭ）对胸腔积液患合同一次胸水细胞ＤＮＡ含量、染色体和病理细胞学的研究表明：１８例癌性胸水的非整倍体ＤＮＡ含量出现率为８３．３３％，１０例结核性胸水均为二倍体ＤＮＡ含量。ＦＣＭ检测细胞ＤＮＡ含量和细胞周期分析方法的诊断阳性率最高，特异性最好，染色体次之，细胞学最低。反复多次细胞学检查可显著提高阳性率。对病理细胞学可疑的病例，有条件可行ＤＮＡ或染色体检查，有助于确诊。
leural effusions from 28 patients were studied bycytology,chromosome and flow-cytometry.Relativecellular DNA content was measured. An estimate ofploidy as well as cyclc distribution has been given.Eighteen patients sufferred from malignant effusionswhile the rest had TB effusions. 83.3% of maligananteffusion had aneuploid.The relative eellular DNAcontent and the cell cycle distribution can providevaluable and decisive information. The study ofchromosome also help the diagnosis in addition tocytological results.
出处
《中华结核和呼吸杂志》
CSCD
北大核心
1994年第2期90-92,T010,共4页
Chinese Journal of Tuberculosis and Respiratory Diseases
关键词
胸膜积液
DNA
染色体
水胸
Flow cytometry Pleural effu-sion DNA Chromosomes
