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阻塞性睡眠呼吸暂停低通气综合征与心律失常的关系 被引量:8

Relationship between Obstructive Sleep Apnea Hypopnea Syndrome and Cardiac Arrhythmia
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摘要 目的探讨阻塞性睡眠呼吸暂停低通气综合征(OSAHS)与心律失常的关系。方法160例睡眠打鼾患者经多导睡眠呼吸监测仪(PSG)进行夜间7h以上睡眠监测并同步监测24h动态心电图,根据PSG监测结果分为98例OSAHS组和62例正常对照组进行对照分析。结果OSAHS组睡眠呼吸暂停低通气指数(AHI)、动态脉搏容积血氧饱和度(SpO2)改变及心律失常发生率较对照组差别有显著意义(P<0.01),伴随着呼吸暂停、SpO2下降心率变化呈周期性改变,SpO2低于80%时心律失常发生率明显增多。结论OSAHS患者夜间睡眠时的低氧血症、自主神经张力的改变是引起心律失常的重要原因。 Objective To investigate the relationship between obstructive sleep apnea hypopnea syndrome(OSAHS) and cardiac arrhythmia. Methods 160 snorers were recruited to undergo more than 7 hours nocturnal polysomnography(PSG) and 24 hours ECG monitoring, and were divided into OSAHS group (n=98) and control group (n=62) based on the results of PSG monitoring. Results There were significant differences in sleep apnea hypopnea index(AHI), SpO_2 and cardiac arrhythmia frequency between the OSAHS and control groups. Accompanying with the breath pause, SpO_2 decreased, and heart rate was periodic changes. The frequency of cardiac arrhythmia obviously increased when SpO_2 was lower than 80%. Conclusion During sleep the low oxygen saturations and fluctuation of autonomic nervous system play important roles in the cardiac arrhythmia in OSAHS patients.
出处 《中国医师杂志》 CAS 2005年第5期600-601,共2页 Journal of Chinese Physician
基金 福建省科技厅科研资助项目(1998-z-163)
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