摘要
目的 观察比较伊贝沙坦与氨氯地平治疗肝阳上亢型高血压病的临床疗效和安全性。方法 采用平行、对照、开放的方法,选取门诊和住院高血压患者按中医辨证标准符合肝阳上亢型者5 9例,分别予伊贝沙坦1 5 0mg 1次/d或氨氯地平5mg 1次/d ,治疗8周,观察降压效果、证候疗效、不良反应、辅助检查的改变。结果 2药降压总有效率分别为90 %和76 %。证候疗效分别为93%和72 %,2组对比有显著性差异(P <0 .0 1 )。结论 与氨氯地平相比,伊贝沙坦不仅在降压上有明显疗效,而且有较好的安全性和耐受性。
Objective It is to observe and compare the clinical effect and safety of irbesartan and amlodipine on liver Yang exuberance syndrome (LYES) hypertension. Methods With paralle, control and exoteric methods, fifty-nine hypertension patients in ambulant clinic and in hospital who accorded with LYES by traditional Chinese medicine differentiation of symptoms and signs criterion were chosen. They were treated with irbesartan 150 mg once a day or amlodipine 5 mg once a day for 8 weeks. The changes of blood pressure, syndrome, untoward reaction and auxiliary examination were observed. Results The total effective rates of lowering blood pressure of the two groups were 90% and 76%. The total effective rates of syndrome of the two groups were 93% and 72%. There were significant difference between the two groups (P<0.01). Conclusion Compared with amlodipine, irbesartan not only has obvious effect on lowering blood pressure, but also has better safety and toleration.
出处
《现代中西医结合杂志》
CAS
2005年第11期1409-1410,共2页
Modern Journal of Integrated Traditional Chinese and Western Medicine
关键词
高血压
肝阳上亢
伊贝沙坦
氨氯地平
hypertension
liver Yang exuberance syndrome
irbesartan
amlodipine
